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{
"metadata": {
"accession": "PF13319",
"entry_id": null,
"type": "family",
"go_terms": null,
"source_database": "pfam",
"member_databases": null,
"integrated": "IPR025149",
"hierarchy": null,
"name": {
"name": "Protein of unknown function (DUF4090)",
"short": "DUF4090"
},
"description": [
{
"text": "<p>This family of proteins is functionally uncharacterised. This family of proteins is found in cyanobacteria. Proteins in this family are approximately 90 amino acids in length. A member of this family, the ssr1528 gene was found to be regulated by an sRNA NsiR4 [[cite:PUB00088099]]. In addition the expression of that gene was repressed under conditions of nitrogen depletion suggesting it may have a role related to cellular nitrogen status [[cite:PUB00088099]].</p>",
"llm": false,
"checked": false,
"updated": false
}
],
"wikipedia": [
{
"title": "Domain_of_unknown_function",
"extract": "<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>",
"thumbnail": null
}
],
"literature": {
"PUB00088099": {
"PMID": 26494284,
"ISBN": null,
"volume": "112",
"issue": "45",
"year": 2015,
"title": "The sRNA NsiR4 is involved in nitrogen assimilation control in cyanobacteria by targeting glutamine synthetase inactivating factor IF7.",
"URL": null,
"raw_pages": "E6243-52",
"medline_journal": "Proc Natl Acad Sci U S A",
"ISO_journal": "Proc. Natl. Acad. Sci. U.S.A.",
"authors": [
"Klahn S",
"Schaal C",
"Georg J",
"Baumgartner D",
"Knippen G",
"Hagemann M",
"Muro-Pastor AM",
"Hess WR."
],
"DOI_URL": "https://doi.org/10.1073/pnas.1508412112"
}
},
"set_info": null,
"overlaps_with": null,
"counters": {
"subfamilies": 0,
"domain_architectures": 1,
"interactions": 0,
"matches": 305,
"pathways": 0,
"proteins": 305,
"proteomes": 188,
"sets": 0,
"structural_models": {
"alphafold": 228,
"bfvd": 0
},
"structures": 0,
"taxa": 654
},
"entry_annotations": {
"hmm": 0,
"logo": 0,
"alignment:seed": 16,
"alignment:full": 161
},
"cross_references": {},
"is_llm": false,
"is_reviewed_llm": false,
"is_updated_llm": false,
"representative_structure": null
}
}
