This family of proteins is functionally uncharacterised. This family of proteins is found in cyanobacteria. Proteins in this family are approximately 90 amino acids in length. A member of this family, the ssr1528 gene was found to be regulated by an sRNA NsiR4 [[cite:PUB00088099]]. In addition the expression of that gene was repressed under conditions of nitrogen depletion suggesting it may have a role related to cellular nitrogen status [[cite:PUB00088099]].
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00088099":{"PMID":26494284,"ISBN":null,"volume":"112","issue":"45","year":2015,"title":"The sRNA NsiR4 is involved in nitrogen assimilation control in cyanobacteria by targeting glutamine synthetase inactivating factor IF7.","URL":null,"raw_pages":"E6243-52","medline_journal":"Proc Natl Acad Sci U S A","ISO_journal":"Proc. Natl. Acad. Sci. U.S.A.","authors":["Klahn S","Schaal C","Georg J","Baumgartner D","Knippen G","Hagemann M","Muro-Pastor AM","Hess WR."],"DOI_URL":"https://doi.org/10.1073/pnas.1508412112"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":305,"pathways":0,"proteins":305,"proteomes":188,"sets":0,"structural_models":{"alphafold":228,"bfvd":0},"structures":0,"taxa":654},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":16,"alignment:full":161},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}