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{
    "metadata": {
        "accession": "PF07648",
        "entry_id": null,
        "type": "domain",
        "go_terms": null,
        "source_database": "pfam",
        "member_databases": null,
        "integrated": "IPR002350",
        "hierarchy": null,
        "name": {
            "name": "Kazal-type serine protease inhibitor domain",
            "short": "Kazal_2"
        },
        "description": [
            {
                "text": "<p>Usually indicative of serine protease inhibitors. However, kazal-like domains are also seen in the extracellular part of agrins, which are not known to be protease inhibitors. Kazal domains often occur in tandem arrays. Small alpha+beta fold containing three disulphides.</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": [
            {
                "title": "Kazal_domain",
                "extract": "<p>The <b>Kazal domain </b> is an evolutionary conserved protein domain usually indicative of serine protease inhibitors. However, kazal-like domains are also seen in the extracellular part of agrins, which are not known to be protease inhibitors.</p>",
                "thumbnail": null
            }
        ],
        "literature": null,
        "set_info": {
            "accession": "CL0005",
            "name": "Kazal"
        },
        "overlaps_with": null,
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 1970,
            "interactions": 0,
            "matches": 81132,
            "pathways": 0,
            "proteins": 44505,
            "proteomes": 1635,
            "sets": 1,
            "structural_models": {
                "alphafold": 37798,
                "bfvd": 0
            },
            "structures": 43,
            "taxa": 5624
        },
        "entry_annotations": {
            "hmm": 0,
            "logo": 0,
            "alignment:seed": 38,
            "alignment:full": 56494
        },
        "cross_references": {},
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": {
            "accession": "3pis",
            "name": "Crystal Structure of Carcinoscorpius rotundicauda Serine Protease Inhibitor Domain 1"
        }
    }
}