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{
    "metadata": {
        "accession": "PF02382",
        "entry_id": null,
        "type": "domain",
        "go_terms": null,
        "source_database": "pfam",
        "member_databases": null,
        "integrated": "IPR018504",
        "hierarchy": null,
        "name": {
            "name": "N-terminal domain in RTX protein",
            "short": "RTX"
        },
        "description": [
            {
                "text": "<p>The RTX family of bacterial toxins are a group of cytolysins and cytotoxins that have RTX (Repeat in ToXin repeats) [pfam:PF00353]. This is a hydrophobic pore-forming domain found at the N-terminal of these proteins [[cite:PUB00100830]].</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00020281": {
                "PMID": 9628576,
                "ISBN": null,
                "volume": "5",
                "issue": "1",
                "year": 1998,
                "title": "Complete nucleotide sequences of 93-kb and 3.3-kb plasmids of an enterohemorrhagic Escherichia coli O157:H7 derived from Sakai outbreak.",
                "URL": null,
                "raw_pages": "1-9",
                "medline_journal": "DNA Res",
                "ISO_journal": "DNA Res.",
                "authors": [
                    "Makino K",
                    "Ishii K",
                    "Yasunaga T",
                    "Hattori M",
                    "Yokoyama K",
                    "Yutsudo CH",
                    "Kubota Y",
                    "Yamaichi Y",
                    "Iida T",
                    "Yamamoto K",
                    "Honda T",
                    "Han CG",
                    "Ohtsubo E",
                    "Kasamatsu M",
                    "Hayashi T",
                    "Kuhara S",
                    "Shinagawa H."
                ],
                "DOI_URL": "http://dx.doi.org/10.1093/dnares/5.1.1"
            },
            "PUB00100830": {
                "PMID": 30405113,
                "ISBN": null,
                "volume": "7",
                "issue": "1",
                "year": 2018,
                "title": "Cytotoxic activity of Kingella kingae RtxA toxin depends on post-translational acylation of lysine residues and cholesterol binding.",
                "URL": null,
                "raw_pages": "178",
                "medline_journal": "Emerg Microbes Infect",
                "ISO_journal": "Emerg Microbes Infect",
                "authors": [
                    "Osickova A",
                    "Balashova N",
                    "Masin J",
                    "Sulc M",
                    "Roderova J",
                    "Wald T",
                    "Brown AC",
                    "Koufos E",
                    "Chang EH",
                    "Giannakakis A",
                    "Lally ET",
                    "Osicka R."
                ],
                "DOI_URL": null
            }
        },
        "set_info": null,
        "overlaps_with": null,
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 16,
            "interactions": 0,
            "matches": 380,
            "pathways": 0,
            "proteins": 380,
            "proteomes": 44,
            "sets": 0,
            "structural_models": {
                "alphafold": 338,
                "bfvd": 0
            },
            "structures": 1,
            "taxa": 208
        },
        "entry_annotations": {
            "hmm": 0,
            "logo": 0,
            "alignment:seed": 5,
            "alignment:full": 21
        },
        "cross_references": {},
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": null
    }
}