{"metadata":{"accession":"PF02382","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR018504","hierarchy":null,"name":{"name":"N-terminal domain in RTX protein","short":"RTX"},"description":[{"text":"<p>The RTX family of bacterial toxins are a group of cytolysins and cytotoxins that have RTX (Repeat in ToXin repeats) [pfam:PF00353]. This is a hydrophobic pore-forming domain found at the N-terminal of these proteins [[cite:PUB00100830]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00020281":{"PMID":9628576,"ISBN":null,"volume":"5","issue":"1","year":1998,"title":"Complete nucleotide sequences of 93-kb and 3.3-kb plasmids of an enterohemorrhagic Escherichia coli O157:H7 derived from Sakai outbreak.","URL":null,"raw_pages":"1-9","medline_journal":"DNA Res","ISO_journal":"DNA Res.","authors":["Makino K","Ishii K","Yasunaga T","Hattori M","Yokoyama K","Yutsudo CH","Kubota Y","Yamaichi Y","Iida T","Yamamoto K","Honda T","Han CG","Ohtsubo E","Kasamatsu M","Hayashi T","Kuhara S","Shinagawa H."],"DOI_URL":"http://dx.doi.org/10.1093/dnares/5.1.1"},"PUB00100830":{"PMID":30405113,"ISBN":null,"volume":"7","issue":"1","year":2018,"title":"Cytotoxic activity of Kingella kingae RtxA toxin depends on post-translational acylation of lysine residues and cholesterol binding.","URL":null,"raw_pages":"178","medline_journal":"Emerg Microbes Infect","ISO_journal":"Emerg Microbes Infect","authors":["Osickova A","Balashova N","Masin J","Sulc M","Roderova J","Wald T","Brown AC","Koufos E","Chang EH","Giannakakis A","Lally ET","Osicka R."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":16,"interactions":0,"matches":380,"pathways":0,"proteins":380,"proteomes":44,"sets":0,"structural_models":{"alphafold":338,"bfvd":0},"structures":1,"taxa":208},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":5,"alignment:full":21},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}