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{
"metadata": {
"accession": "cd22332",
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"type": "domain",
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"source_database": "cdd",
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"name": {
"name": "N-terminal domain of HsdR motor subunit of type I restriction-modification enzyme EcoR124I and similar systems",
"short": "HsdR_N"
},
"description": [
{
"text": "<p>The N-terminal endonuclease-like domain of HsdR motor subunit of type I restriction-modification enzyme EcoR124I belongs to a wider superfamily of PDDEXK nucleases including very short patch repair (Vsr) endonucleases, archaeal Holliday junction resolvases, MutH methyl-directed DNA mismatch-repair endonucleases, and catalytic domains of many restriction endonucleases, such as EcoRI, BamHI, and FokI. [[cite:PUB00049980], [cite:PUB00147257], [cite:PUB00110635], [cite:PUB00110634]]</p>",
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"volume": "16",
"issue": "1",
"year": 2009,
"title": "Structure of the motor subunit of type I restriction-modification complex EcoR124I.",
"URL": null,
"raw_pages": "94-5",
"medline_journal": "Nat Struct Mol Biol",
"ISO_journal": "Nat. Struct. Mol. Biol.",
"authors": [
"Lapkouski M",
"Panjikar S",
"Janscak P",
"Smatanova IK",
"Carey J",
"Ettrich R",
"Csefalvay E."
],
"DOI_URL": "http://dx.doi.org/10.1038/nsmb.1523"
},
"PUB00147257": {
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"volume": "384",
"issue": "5",
"year": 2008,
"title": "The interrelationship of helicase and nuclease domains during DNA translocation by the molecular motor EcoR124I.",
"URL": null,
"raw_pages": "1273-86",
"medline_journal": "J Mol Biol",
"ISO_journal": "J Mol Biol",
"authors": [
"Sisakova E",
"Weiserova M",
"Dekker C",
"Seidel R",
"Szczelkun MD."
],
"DOI_URL": null
},
"PUB00110635": {
"PMID": 14529527,
"ISBN": null,
"volume": "4",
"issue": "5",
"year": 2003,
"title": "Crystallographic and bioinformatic studies on restriction endonucleases: inference of evolutionary relationships in the \"midnight zone\" of homology.",
"URL": null,
"raw_pages": "327-37",
"medline_journal": "Curr Protein Pept Sci",
"ISO_journal": "Curr Protein Pept Sci",
"authors": [
"Bujnicki JM."
],
"DOI_URL": null
},
"PUB00110634": {
"PMID": 10654258,
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"volume": "50",
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"year": 2000,
"title": "Phylogeny of the restriction endonuclease-like superfamily inferred from comparison of protein structures.",
"URL": null,
"raw_pages": "39-44",
"medline_journal": "J Mol Evol",
"ISO_journal": "J Mol Evol",
"authors": [
"Bujnicki JM."
],
"DOI_URL": null
}
},
"set_info": {
"accession": "cl40440",
"name": "PDDEXK_nuclease-like"
},
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},
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},
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"is_llm": false,
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}
}
