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Cellular Phenotype Database


Gene summary: TRAM1

Gene information:
Synonyms:
TRAM, TRAMP
Gene description:
translocation associated membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:20568] 
Ensembl ID:
ENSG00000067167
Protein domains:
(provided by InterPro)
show
Gene Ontology:
show
Phenotypes observed:
Observed phenotypes (?): Assigned ontology terms (?): Screen (?) Reagent ID (?)
AMBN10027070 DHARM0018870
Increased oscillation
  • Increased frequency of negative regulation of NF-kappaB transcription factor activity
    synonyms: 
    Increased NF-kB oscillation
    		• N1_SyM_1
    Mild inhibition of secretion
  • Mild decrease in rate of protein secretion
    synonyms: 
    Mild inhibition of protein secretion
    		• E1_SyM_1
    All genes with the same set of phenotypes (number of genes / number of reagents):
    phenotype view
    ontology view
    		 2136 / 2271
    Phenotype set for these genes/reagents:
    — Mild inhibition of secretion
    Ontology set for these genes/reagents:
    — Mild decrease in rate of protein secretion
    		86 / 114
    Phenotype set for these genes/reagents:
    — Increased oscillation
    Ontology set for these genes/reagents:
    — Increased frequency of negative regulation of NF-kappaB transcription factor activity
     1 .. 0.5 
      — evidence (reproducibility)
    Reagents with no phenotype:

    Reagents, targeting this gene, but with no phenotype revealed (or revealed with low evidence) for the following screens:

    Reagent Screen ID Study Title Screen type
    AMBN10027069 B1_SyM_1 BZH_SH4-mCherry-GFP Primary
    AMBN10027069 M1_SyM_1 Mitocheck Primary
    AMBN10027070 B1_SyM_1 BZH_SH4-mCherry-GFP Primary
    AMBN10027070 M1_SyM_1 Mitocheck Primary