Gene summary: sequence, alignment information, cellular phenotypes observed

Gene summary: EXTL3

Gene information:

Gene description:: exostosin-like glycosyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:3518]

Protein domains: (provided by InterPro)

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Gene Ontology:

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Phenotypes observed:

Observed phenotypes (?): These terms represent the phenotypic classes observed following the suppression of the expression of the selected gene across independent screens	Assigned ontology terms (?): These terms represent the cellular phenotype ontology terms assigned to the observed phenotypes	Screen (?) Screen ID link to additional information available for each study and screen	Reagent ID (?) Each identifier represents a reagent that was used in a particular screen to suppress the expression of its target gene and for which a phenotype has been observed. The reagents listed here uniquely map to their target gene. The reagent ID displayed is the SysMicro internal ID
			AMBN10011889
Dynamic changes	Increased variability of nuclear shape in population synonyms: Variable cell shape	M1_SyM_1	0.66
Large	Increased nucleus size synonyms: Increased DNA area Large nuclei Large nucleus	M1_SyM_1	0.66
All genes with the same set of phenotypes (number of genes / number of reagents):		phenotype view ontology view	2 / 2 Phenotype set for these genes/reagents: — Dynamic changes — Large 2 / 2 Ontology set for these genes/reagents: — Increased variability of nuclear shape in population — Increased nucleus size

1 .. 0.5

— evidence (reproducibility)

Not unique targeting:

List of reagents also targeting this gene, but not uniquely (?)

Reagents with no phenotype:

Reagents, targeting this gene, but with no phenotype revealed (or revealed with low evidence) for the following screens: