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CHEBI:9943 - venlafaxine
| Formula | C17H27NO2 |
| Net Charge | 0 |
| Average Mass | 277.408 |
| Monoisotopic Mass | 277.20418 |
| SMILES | COc1ccc(C(CN(C)C)C2(O)CCCCC2)cc1 |
| InChI | InChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10,16,19H,4-6,11-13H2,1-3H3 |
| InChIKey | PNVNVHUZROJLTJ-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Chemical Roles: | environmental contaminant Any minor or unwanted substance introduced into the environment that can have undesired effects. Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | xenobiotic A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. serotonin uptake inhibitor A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. adrenergic uptake inhibitor Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin. dopamine uptake inhibitor A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. |
| Applications: | serotonin uptake inhibitor A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. adrenergic uptake inhibitor Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin. dopamine uptake inhibitor A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| venlafaxine (CHEBI:9943) has role adrenergic uptake inhibitor (CHEBI:35640) |
| venlafaxine (CHEBI:9943) has role analgesic (CHEBI:35480) |
| venlafaxine (CHEBI:9943) has role antidepressant (CHEBI:35469) |
| venlafaxine (CHEBI:9943) has role dopamine uptake inhibitor (CHEBI:51039) |
| venlafaxine (CHEBI:9943) has role environmental contaminant (CHEBI:78298) |
| venlafaxine (CHEBI:9943) has role serotonin uptake inhibitor (CHEBI:50949) |
| venlafaxine (CHEBI:9943) has role xenobiotic (CHEBI:35703) |
| venlafaxine (CHEBI:9943) is a cyclohexanols (CHEBI:23480) |
| venlafaxine (CHEBI:9943) is a monomethoxybenzene (CHEBI:25235) |
| venlafaxine (CHEBI:9943) is a tertiary alcohol (CHEBI:26878) |
| venlafaxine (CHEBI:9943) is a tertiary amino compound (CHEBI:50996) |
| Incoming Relation(s) |
| venlafaxine hydrochloride (CHEBI:9944) has part venlafaxine (CHEBI:9943) |
| IUPAC Name |
|---|
| 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol |
| INNs | Source |
|---|---|
| venlafaxina | WHO MedNet |
| venlafaxine | WHO MedNet |
| venlafaxine | ChemIDplus |
| venlafaxinum | WHO MedNet |
| Synonyms | Source |
|---|---|
| Elafax | ChemIDplus |
| Venlafaxine | KEGG COMPOUND |
| Manual Xrefs | Databases |
|---|---|
| 2813 | DrugCentral |
| C07187 | KEGG COMPOUND |
| D08670 | KEGG DRUG |
| DB00285 | DrugBank |
| HMDB0005016 | HMDB |
| LSM-1616 | LINCS |
| Venlafaxine | Wikipedia |
| Registry Numbers | Sources |
|---|---|
| Reaxys:4234848 | Reaxys |
| CAS:93413-69-5 | KEGG COMPOUND |
| CAS:93413-69-5 | ChemIDplus |
| Citations |
|---|