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CHEBI:9927 - valsartan
| Formula | C24H29N5O3 |
| Net Charge | 0 |
| Average Mass | 435.528 |
| Monoisotopic Mass | 435.22704 |
| SMILES | CCCCC(=O)N(Cc1ccc(-c2ccccc2-c2nnnn2)cc1)[C@H](C(=O)O)C(C)C |
| InChI | InChI=1S/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m0/s1 |
| InChIKey | ACWBQPMHZXGDFX-QFIPXVFZSA-N |
| Wikipedia |
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| Roles Classification |
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| Chemical Roles: | environmental contaminant Any minor or unwanted substance introduced into the environment that can have undesired effects. Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Brønsted base). |
| Biological Roles: | angiotensin receptor antagonist A hormone antagonist that blocks angiotensin receptors. antiviral agent A substance that destroys or inhibits replication of viruses. xenobiotic A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. |
| Applications: | anti-arrhythmia drug A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. hypoglycemic agent A drug which lowers the blood glucose level. angiotensin receptor antagonist A hormone antagonist that blocks angiotensin receptors. antiatherosclerotic agent A cardiovascular drug that prevents atherosclerosis (a disease in which the inside of an artery narrows due to the build up of plaque). Compare with antiatherogenic agent. renoprotective agent Any compound that is able to prevent damage to the kidneys. antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| valsartan (CHEBI:9927) has role angiotensin receptor antagonist (CHEBI:61016) |
| valsartan (CHEBI:9927) has role anti-arrhythmia drug (CHEBI:38070) |
| valsartan (CHEBI:9927) has role antiatherosclerotic agent (CHEBI:145947) |
| valsartan (CHEBI:9927) has role antihypertensive agent (CHEBI:35674) |
| valsartan (CHEBI:9927) has role antiviral agent (CHEBI:22587) |
| valsartan (CHEBI:9927) has role cardiovascular drug (CHEBI:35554) |
| valsartan (CHEBI:9927) has role environmental contaminant (CHEBI:78298) |
| valsartan (CHEBI:9927) has role hypoglycemic agent (CHEBI:35526) |
| valsartan (CHEBI:9927) has role renoprotective agent (CHEBI:231911) |
| valsartan (CHEBI:9927) has role xenobiotic (CHEBI:35703) |
| valsartan (CHEBI:9927) is a biphenylyltetrazole (CHEBI:48420) |
| valsartan (CHEBI:9927) is a monocarboxylic acid (CHEBI:25384) |
| valsartan (CHEBI:9927) is a monocarboxylic acid amide (CHEBI:29347) |
| Incoming Relation(s) |
| Byvalson (CHEBI:132911) has part valsartan (CHEBI:9927) |
| IUPAC Name |
|---|
| N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-L-valine |
| INN | Source |
|---|---|
| valsartan | ChemIDplus |
| Synonyms | Source |
|---|---|
| Diovan | KEGG DRUG |
| N-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine | ChemIDplus |
| N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine | IUPAC |
| (S)-N-valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine | IUPHAR |
| NSC-758927 | ChEMBL |
| Brand Names | Source |
|---|---|
| Prexxartan | ChEMBL |
| Valsartan component of agsav301 | ChEMBL |
| Valsartan component of byvalson | ChEMBL |
| Valsartan component of copalia | ChEMBL |
| Valsartan component of copalia-hct | ChEMBL |
| Valsartan component of dafiro | ChEMBL |
| Registry Numbers | Sources |
|---|---|
| Reaxys:7754038 | Reaxys |
| CAS:137862-53-4 | ChemIDplus |
| Citations |
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