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CHEBI:9671 - triamterene

ChEBI IDCHEBI:9671
ChEBI Nametriamterene
Stars
DefinitionPteridine substituted at positions 2, 4 and 7 with amino groups and at position 6 with a phenyl group. A sodium channel blocker, it is used as a diuretic in the treatment of hypertension and oedema.
Secondary ChEBI IDCHEBI:93604
Last Modified20 June 2017
DownloadsMolfile
FormulaC12H11N7
Net Charge0
Average Mass253.269
Monoisotopic Mass253.10759
SMILESNc1nc(N)c2nc(-c3ccccc3)c(N)nc2n1
InChIInChI=1S/C12H11N7/c13-9-7(6-4-2-1-3-5-6)16-8-10(14)18-12(15)19-11(8)17-9/h1-5H,(H6,13,14,15,17,18,19)
InChIKeyFNYLWPVRPXGIIP-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Role:
sodium channel blocker  An agent that inhibits sodium influx through cell membranes.
Application:
diuretic  An agent that promotes the excretion of urine through its effects on kidney function.
ChEBI Ontology
Outgoing Relation(s)
triamterene (CHEBI:9671) has role diuretic (CHEBI:35498)
triamterene (CHEBI:9671) has role sodium channel blocker (CHEBI:38633)
triamterene (CHEBI:9671) is a pteridines (CHEBI:26373)
IUPAC Name 
6-phenylpteridine-2,4,7-triamine
INNs  Source
triamtereneChemIDplus
triamterenumChemIDplus
triamterenaChemIDplus
Manual XrefsDatabases
D00386KEGG DRUG
LSM-4060LINCS
2728DrugCentral
TriamtereneWikipedia
Registry NumbersSources
CAS:396-01-0ChemIDplus
Citations