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CHEBI:27999 - tolbutamide
| Formula | C12H18N2O3S |
| Net Charge | 0 |
| Average Mass | 270.354 |
| Monoisotopic Mass | 270.10381 |
| SMILES | CCCCNC(=O)NS(=O)(=O)c1ccc(C)cc1 |
| InChI | InChI=1S/C12H18N2O3S/c1-3-4-9-13-12(15)14-18(16,17)11-7-5-10(2)6-8-11/h5-8H,3-4,9H2,1-2H3,(H2,13,14,15) |
| InChIKey | JLRGJRBPOGGCBT-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Homo sapiens (ncbitaxon:9606) | - | DOI (10.1038/nbt.2488) |
| Roles Classification |
|---|
| Biological Roles: | antiviral agent A substance that destroys or inhibits replication of viruses. potassium channel blocker An agent that inhibits cell membrane glycoproteins that are selectively permeable to potassium ions. human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). insulin secretagogue A secretagogue that causes the secretion of insulin. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. |
| Applications: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. hypoglycemic agent A drug which lowers the blood glucose level. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| tolbutamide (CHEBI:27999) has role analgesic (CHEBI:35480) |
| tolbutamide (CHEBI:27999) has role antineoplastic agent (CHEBI:35610) |
| tolbutamide (CHEBI:27999) has role antiviral agent (CHEBI:22587) |
| tolbutamide (CHEBI:27999) has role human metabolite (CHEBI:77746) |
| tolbutamide (CHEBI:27999) has role hypoglycemic agent (CHEBI:35526) |
| tolbutamide (CHEBI:27999) has role insulin secretagogue (CHEBI:90415) |
| tolbutamide (CHEBI:27999) has role potassium channel blocker (CHEBI:50509) |
| tolbutamide (CHEBI:27999) is a N-sulfonylurea (CHEBI:76983) |
| IUPAC Name |
|---|
| N-[(butylamino)carbonyl]-4-methylbenzenesulfonamide |
| INNs | Source |
|---|---|
| tolbutamida | ChemIDplus |
| tolbutamide | ChemIDplus |
| tolbutamidum | ChemIDplus |
| Synonyms | Source |
|---|---|
| 1-Butyl-3-(p-methylphenylsulfonyl)urea | ChemIDplus |
| 1-Butyl-3-(p-tolylsulfonyl)urea | ChemIDplus |
| 1-Butyl-3-tosylurea | ChemIDplus |
| 1-p-Toluenesulfonyl-3-butylurea | ChemIDplus |
| 3-(p-Tolyl-4-sulfonyl)-1-butylurea | ChemIDplus |
| Butamide | ChEMBL |
| Brand Names | Source |
|---|---|
| Glyconon | ChEMBL |
| Orinase | ChEMBL |
| Pramidex | ChEMBL |
| Rastinon | ChEMBL |
| Citations |
|---|