CHEBI:9611 - tocainide

ChEBI IDCHEBI:9611
ChEBI Nametocainide
Stars
DefinitionA monocarboxylic acid amide in which 2,6-dimethylphenylaniline and isobutyric acid have combined to form the amide bond; used as a local anaesthetic.
Secondary ChEBI IDCHEBI:106722
Last Modified22 February 2017
DownloadsMolfile
FormulaC11H16N2O
Net Charge0
Average Mass192.262
Monoisotopic Mass192.12626
SMILESCc1cccc(C)c1NC(=O)C(C)N
InChIInChI=1S/C11H16N2O/c1-7-5-4-6-8(2)10(7)13-11(14)9(3)12/h4-6,9H,12H2,1-3H3,(H,13,14)
InChIKeyBUJAGSGYPOAWEI-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Role:
sodium channel blocker  An agent that inhibits sodium influx through cell membranes.
Applications:
anti-arrhythmia drug  A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
local anaesthetic  Any member of a group of drugs that reversibly inhibit the propagation of signals along nerves. Wide variations in potency, stability, toxicity, water-solubility and duration of action determine the route used for administration, e.g. topical, intravenous, epidural or spinal block.
ChEBI Ontology
Outgoing Relation(s)
tocainide (CHEBI:9611) has role anti-arrhythmia drug (CHEBI:38070)
tocainide (CHEBI:9611) has role local anaesthetic (CHEBI:36333)
tocainide (CHEBI:9611) has role sodium channel blocker (CHEBI:38633)
tocainide (CHEBI:9611) is a monocarboxylic acid amide (CHEBI:29347)
IUPAC Name 
N-(2,6-dimethylphenyl)alaninamide
INNs  Source
tocainideChemIDplus
tocainidaChemIDplus
tocainidumChemIDplus
Synonyms  Source
2-Amino-2',6'-propionoxylidideChemIDplus
2-Amino-N-(2,6-dimethylphenyl)propionamidChemIDplus
Alanyl-2,6-xylidideChemIDplus
2-amino-N-(2,6-dimethylphenyl)propanamideChEBI
Manual XrefsDatabases
C07142KEGG COMPOUND
D06172KEGG DRUG
DB01056DrugBank
TocainideWikipedia
LSM-1909LINCS
2686DrugCentral
Registry NumbersSources
Reaxys:2416564Reaxys
CAS:41708-72-9KEGG COMPOUND
CAS:41708-72-9ChemIDplus
Citations