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CHEBI:9451 - terconazole
| ChEBI ID | CHEBI:9451 |
| ChEBI Name | terconazole |
| Stars | |
| Definition | A racemate consisting of equimolar amounts of (2R,4S)- and (2S,4R)-terconazole. It has broad-spectrum antifungal activitiy and is used for the treatment of vaginal yeast infections (Candida). |
| Last Modified | 23 April 2020 |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | anticoronaviral agent Any antiviral agent which inhibits the activity of coronaviruses. antifungal drug Any antifungal agent used to prevent or treat fungal infections in humans or animals. ergosterol biosynthesis inhibitor Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol. antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. antifungal drug Any antifungal agent used to prevent or treat fungal infections in humans or animals. antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. ergosterol biosynthesis inhibitor Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol. antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. |
| Applications: | antifungal drug Any antifungal agent used to prevent or treat fungal infections in humans or animals. antifungal drug Any antifungal agent used to prevent or treat fungal infections in humans or animals. |
| ChEBI Ontology |
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| Outgoing Relation(s) |
| terconazole (CHEBI:9451) has part (2R,4S)-terconazole (CHEBI:82980) |
| terconazole (CHEBI:9451) has part (2S,4R)-terconazole (CHEBI:82981) |
| terconazole (CHEBI:9451) has role anticoronaviral agent (CHEBI:149553) |
| terconazole (CHEBI:9451) is a conazole antifungal drug (CHEBI:87071) |
| terconazole (CHEBI:9451) is a racemate (CHEBI:60911) |
| terconazole (CHEBI:9451) is a triazole antifungal drug (CHEBI:87101) |
| IUPAC Name |
|---|
| rac-1-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-isopropylpiperazine |
| INNs | Source |
|---|---|
| terconazol | WHO MedNet |
| terconazole | WHO MedNet |
| terconazole | WHO MedNet |
| terconazolum | WHO MedNet |
| Synonyms | Source |
|---|---|
| cis-1-(p-{[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-isopropylpiperazine | ChemIDplus |
| R 42,470 | ChemIDplus |
| R-42,470 | ChemIDplus |
| R-42470 | ChEBI |
| Brand Names | Source |
|---|---|
| Terazol 7 | ChEBI |
| Terazol 3 | KEGG DRUG |
| Manual Xrefs | Databases |
|---|---|
| C08080 | KEGG COMPOUND |
| D00888 | KEGG DRUG |
| DB00251 | DrugBank |
| Terconazole | Wikipedia |
| HMDB0014396 | HMDB |
| Registry Numbers | Sources |
|---|---|
| Reaxys:7471103 | Reaxys |
| CAS:67915-31-5 | KEGG COMPOUND |
| CAS:67915-31-5 | ChemIDplus |
| Citations |
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