CHEBI:9435 - Temazepam

ChEBI IDCHEBI:9435
ChEBI NameTemazepam
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Last Modified22 February 2017
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FormulaC16H13ClN2O2
Net Charge0
Average Mass300.745
Monoisotopic Mass300.06656
SMILESCN1C(=O)C(O)N=C(c2ccccc2)c2cc(Cl)ccc21
InChIInChI=1S/C16H13ClN2O2/c1-19-13-8-7-11(17)9-12(13)14(18-15(20)16(19)21)10-5-3-2-4-6-10/h2-9,15,20H,1H3
InChIKeySEQDDYPDSLOBDC-UHFFFAOYSA-N
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
Temazepam (CHEBI:9435) is a benzodiazepine (CHEBI:22720)
Synonyms  Source
TemazepamKEGG COMPOUND
Restoril (TN)KEGG COMPOUND
levanxolDrugCentral
(RS)-TemazepamDrugCentral
levanxeneDrugCentral
Manual XrefsDatabases
C07125KEGG COMPOUND
D00370KEGG DRUG
2585DrugCentral
HMDB0014376HMDB
Registry NumbersSources
CAS:846-50-4KEGG COMPOUND