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CHEBI:9399 - tamsulosin hydrochloride

Default Structure
ChEBI IDCHEBI:9399
ChEBI Nametamsulosin hydrochloride
Stars
DefinitionA hydrochloride resulting from the reaction of equimolar amounts of tamulosin and hydrogen chloride.
Last Modified13 November 2018
DownloadsMolfile
FormulaC20H28N2O5S.HCl
Net Charge0
Average Mass444.981
Monoisotopic Mass444.14857
SMILESCCOc1ccccc1OCCN[C@H](C)Cc1ccc(OC)c(S(N)(=O)=O)c1.Cl
InChIInChI=1S/C20H28N2O5S.ClH/c1-4-26-17-7-5-6-8-18(17)27-12-11-22-15(2)13-16-9-10-19(25-3)20(14-16)28(21,23)24;/h5-10,14-15,22H,4,11-13H2,1-3H3,(H2,21,23,24);1H/t15-;/m1./s1
InChIKeyZZIZZTHXZRDOFM-XFULWGLBSA-N
Roles Classification
Biological Role:
alpha-adrenergic antagonist  An agent that binds to but does not activate α-adrenergic receptors thereby blocking the actions of endogenous or exogenous α-adrenergic agonists. α-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
Applications:
alpha-adrenergic antagonist  An agent that binds to but does not activate α-adrenergic receptors thereby blocking the actions of endogenous or exogenous α-adrenergic agonists. α-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
tamsulosin hydrochloride (CHEBI:9399) has part tamsulosin(1+) (CHEBI:142544)
tamsulosin hydrochloride (CHEBI:9399) has role antineoplastic agent (CHEBI:35610)
tamsulosin hydrochloride (CHEBI:9399) has role α-adrenergic antagonist (CHEBI:37890)
tamsulosin hydrochloride (CHEBI:9399) is a hydrochloride (CHEBI:36807)
tamsulosin hydrochloride (CHEBI:9399) is enantiomer of ent-tamsulosin hydrochloride (CHEBI:142550)
Incoming Relation(s)
rac-tamsulosin hydrochloride (CHEBI:142565) has part tamsulosin hydrochloride (CHEBI:9399)
rac-tamulosin hydrochloride (CHEBI:142553) has part tamsulosin hydrochloride (CHEBI:9399)
ent-tamsulosin hydrochloride (CHEBI:142550) is enantiomer of tamsulosin hydrochloride (CHEBI:9399)
IUPAC Name 
5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonamide hydrochloride
Synonyms  Source
R-(−)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide hydrochlorideChemIDplus
(−)-(R)-5-(2-((2-(o-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide monohydrochlorideChemIDplus
LY253351ChemIDplus
YM 617ChemIDplus
Brand Names  Source
FlomaxKEGG DRUG
HarnalKEGG DRUG
(R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide monohydrochlorideChemIDplus
OmnicChemIDplus
PradifChemIDplus
Manual XrefsDatabases
2562DrugCentral
D01024KEGG DRUG
DB00706DrugBank
WO2007031823Patent
Registry NumbersSources
Beilstein:6897600Beilstein
CAS:106463-17-6ChemIDplus