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CHEBI:93715 - 7-chloro-5,10-dihydrothieno[3,4-b][1,5]benzodiazepin-4-one

ChEBI IDCHEBI:93715
ChEBI Name7-chloro-5,10-dihydrothieno[3,4-b][1,5]benzodiazepin-4-one
Stars
DownloadsMolfile
FormulaC11H7ClN2OS
Net Charge0
Average Mass250.710
Monoisotopic Mass249.99676
SMILESO=C1Nc2cc(Cl)ccc2Nc2cscc21
InChIInChI=1S/C11H7ClN2OS/c12-6-1-2-8-9(3-6)14-11(15)7-4-16-5-10(7)13-8/h1-5,13H,(H,14,15)
InChIKeyPHNFXXZEKWQHDX-UHFFFAOYSA-N
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
7-chloro-5,10-dihydrothieno[3,4-b][1,5]benzodiazepin-4-one (CHEBI:93715) is a benzodiazepine (CHEBI:22720)
Manual XrefsDatabases
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