CHEBI:9331 - sulfamethizole

ChEBI IDCHEBI:9331
ChEBI Namesulfamethizole
Stars
DefinitionA sulfonamide consisting of a 1,3,4-thiadiazole nucleus with a methyl substituent at C-5 and a 4-aminobenzenesulfonamido group at C-2.
Last Modified12 March 2019
DownloadsMolfile
FormulaC9H10N4O2S2
Net Charge0
Average Mass270.339
Monoisotopic Mass270.02452
SMILESCc1nnc(NS(=O)(=O)c2ccc(N)cc2)s1
InChIInChI=1S/C9H10N4O2S2/c1-6-11-12-9(16-6)13-17(14,15)8-4-2-7(10)3-5-8/h2-5H,10H2,1H3,(H,12,13)
InChIKeyVACCAVUAMIDAGB-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Roles:
antibacterial agent  A substance (or active part thereof) that kills or slows the growth of bacteria.
antimicrobial agent  A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
EC 2.5.1.15 (dihydropteroate synthase) inhibitor  An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of dihydropteroate synthase (EC 2.5.1.15), an enzyme that catalyzes the formation of dihydropteroate from p-aminobenzoic acid and dihydropteridine-hydroxymethyl-pyrophosphate.
drug allergen  Any drug which causes the onset of an allergic reaction.
antimicrobial agent  A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
Applications:
antiinfective agent  A substance used in the prophylaxis or therapy of infectious diseases.
ophthalmology drug  Any compound used for the treatment of eye conditions or eye diseases.
drug allergen  Any drug which causes the onset of an allergic reaction.
ChEBI Ontology
Outgoing Relation(s)
sulfamethizole (CHEBI:9331) has role antibacterial agent (CHEBI:33282)
sulfamethizole (CHEBI:9331) has role antiinfective agent (CHEBI:35441)
sulfamethizole (CHEBI:9331) has role antimicrobial agent (CHEBI:33281)
sulfamethizole (CHEBI:9331) has role drug allergen (CHEBI:88188)
sulfamethizole (CHEBI:9331) has role EC 2.5.1.15 (dihydropteroate synthase) inhibitor (CHEBI:50502)
sulfamethizole (CHEBI:9331) has role ophthalmology drug (CHEBI:66981)
sulfamethizole (CHEBI:9331) is a sulfonamide (CHEBI:35358)
sulfamethizole (CHEBI:9331) is a sulfonamide antibiotic (CHEBI:87228)
sulfamethizole (CHEBI:9331) is a thiadiazoles (CHEBI:38099)
IUPAC Name 
4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide
INNs  Source
sulfaméthizolChEBI
sulfamethizoleChemIDplus
sulfamethizolumChemIDplus
sulfametizolChemIDplus
Synonyms  Source
NSC-757327ChEMBL
SulfamethizoleKEGG COMPOUND
sulfamethylthiadiazoleChEBI
sulphamethazoleChEBI
sulphamethiozoleChEBI
Brand Names  Source
MethazolChEMBL
MicrosulChEMBL
ProklarChEMBL
RufolDrugBank
SulphamethylthiadiazoleChEMBL
TetracidChEMBL
Manual XrefsDatabases
2512DrugCentral
C08050KEGG COMPOUND
D00870KEGG DRUG
DB00576DrugBank
LSM-5455LINCS
SulfamethizoleWikipedia
US2447702Patent
Registry NumbersSources
Reaxys:255002Reaxys
CAS:144-82-1ChemIDplus
Citations