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CHEBI:9331 - sulfamethizole

ChEBI IDCHEBI:9331
ChEBI Namesulfamethizole
Stars
DefinitionA sulfonamide consisting of a 1,3,4-thiadiazole nucleus with a methyl substituent at C-5 and a 4-aminobenzenesulfonamido group at C-2.
Last Modified12 March 2019
DownloadsMolfile
FormulaC9H10N4O2S2
Net Charge0
Average Mass270.339
Monoisotopic Mass270.02452
SMILESCc1nnc(NS(=O)(=O)c2ccc(N)cc2)s1
InChIInChI=1S/C9H10N4O2S2/c1-6-11-12-9(16-6)13-17(14,15)8-4-2-7(10)3-5-8/h2-5H,10H2,1H3,(H,12,13)
InChIKeyVACCAVUAMIDAGB-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Roles:
drug allergen  Any drug which causes the onset of an allergic reaction.
EC 2.5.1.15 (dihydropteroate synthase) inhibitor  An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of dihydropteroate synthase (EC 2.5.1.15), an enzyme that catalyzes the formation of dihydropteroate from p-aminobenzoic acid and dihydropteridine-hydroxymethyl-pyrophosphate.
antimicrobial agent  A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
antimicrobial agent  A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
Applications:
drug allergen  Any drug which causes the onset of an allergic reaction.
antiinfective agent  A substance used in the prophylaxis or therapy of infectious diseases.
ChEBI Ontology
Outgoing Relation(s)
sulfamethizole (CHEBI:9331) has role antiinfective agent (CHEBI:35441)
sulfamethizole (CHEBI:9331) has role antimicrobial agent (CHEBI:33281)
sulfamethizole (CHEBI:9331) has role drug allergen (CHEBI:88188)
sulfamethizole (CHEBI:9331) has role EC 2.5.1.15 (dihydropteroate synthase) inhibitor (CHEBI:50502)
sulfamethizole (CHEBI:9331) is a sulfonamide (CHEBI:35358)
sulfamethizole (CHEBI:9331) is a sulfonamide antibiotic (CHEBI:87228)
sulfamethizole (CHEBI:9331) is a thiadiazoles (CHEBI:38099)
IUPAC Name 
4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide
INNs  Source
sulfamethizoleChemIDplus
sulfaméthizolChEBI
sulfamethizolumChemIDplus
sulfametizolChemIDplus
Synonyms  Source
SulfamethizoleKEGG COMPOUND
sulfamethylthiadiazoleChEBI
sulphamethiozoleChEBI
sulphamethazoleChEBI
Brand Name  Source
RufolDrugBank
Manual XrefsDatabases
C08050KEGG COMPOUND
D00870KEGG DRUG
DB00576DrugBank
US2447702Patent
SulfamethizoleWikipedia
LSM-5455LINCS
2512DrugCentral
Registry NumbersSources
Reaxys:255002Reaxys
CAS:144-82-1ChemIDplus
Citations