EMBL-EBI | Chemical Biology | ChEBI
Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search
CHEBI:15746 - spermine
| Formula | C10H26N4 |
| Net Charge | 0 |
| Average Mass | 202.346 |
| Monoisotopic Mass | 202.21575 |
| SMILES | NCCCNCCCCNCCCN |
| InChI | InChI=1S/C10H26N4/c11-5-3-9-13-7-1-2-8-14-10-4-6-12/h13-14H,1-12H2 |
| InChIKey | PFNFFQXMRSDOHW-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Daphnia magna (ncbitaxon:35525) | - | Article (Mixtures of similarly acting compounds in Daphnia magna: From gene to metabolite and beyondTine Vandenbrouck, Oliver A.H. Jones, Nathalie Dom, Julian L. Griffin, Wim De CoenEnvironment International 36 (2010) 254-268) | |
| Mus musculus (ncbitaxon:10090) | - | PubMed (19425150) | Source: BioModels - MODEL1507180067 |
| Roles Classification |
|---|
| Chemical Roles: | antioxidant A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. fundamental metabolite Any metabolite produced by all living cells. |
| Application: | immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| spermine (CHEBI:15746) has role antioxidant (CHEBI:22586) |
| spermine (CHEBI:15746) has role fundamental metabolite (CHEBI:78675) |
| spermine (CHEBI:15746) has role immunosuppressive agent (CHEBI:35705) |
| spermine (CHEBI:15746) is a polyazaalkane (CHEBI:39474) |
| spermine (CHEBI:15746) is a tetramine (CHEBI:39166) |
| spermine (CHEBI:15746) is conjugate base of spermine(4+) (CHEBI:45725) |
| Incoming Relation(s) |
| N4-aminopropylspermine (CHEBI:83554) has functional parent spermine (CHEBI:15746) |
| substituted spermine (CHEBI:26735) has functional parent spermine (CHEBI:15746) |
| spermine(4+) (CHEBI:45725) is conjugate acid of spermine (CHEBI:15746) |
| IUPAC Name |
|---|
| N,N'-bis(3-aminopropyl)butane-1,4-diamine |
| Synonyms | Source |
|---|---|
| 4,9-diaza-1,12-dodecanediamine | NIST Chemistry WebBook |
| 4,9-diazadodecane-1,12-diamine | NIST Chemistry WebBook |
| N,N'-Bis(3-aminopropyl)-1,4-butanediamine | KEGG COMPOUND |
| Spermine | KEGG COMPOUND |
| SPERMINE | PDBeChem |
| Citations |
|---|