EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:92184 - GW405833

ChEBI IDCHEBI:92184
ChEBI NameGW405833
Stars
DefinitionA methylindole that is 2-methyl-1H-indole substituted by 2,3-dichlorobenzoyl, 2-(morpholin-4-yl)ethyl, and methoxy groups at positions 1, 3 and 5, respectively. It is a partial agonist of the cannabinoid CB2 receptor (EC50 = 0.65 nM).
Last Modified5 July 2024
DownloadsMolfile
FormulaC23H24Cl2N2O3
Net Charge0
Average Mass447.362
Monoisotopic Mass446.11640
SMILESCOc1ccc2c(c1)c(CCN1CCOCC1)c(C)n2C(=O)c1cccc(Cl)c1Cl
InChIInChI=1S/C23H24Cl2N2O3/c1-15-17(8-9-26-10-12-30-13-11-26)19-14-16(29-2)6-7-21(19)27(15)23(28)18-4-3-5-20(24)22(18)25/h3-7,14H,8-13H2,1-2H3
InChIKeyFSFZRNZSZYDVLI-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Roles:
CB2 receptor agonist  A cannabinoid receptor agonist that binds to and activates type 2 cannabinoid receptors.
analgesic  An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
Applications:
anti-inflammatory agent  Any compound that has anti-inflammatory effects.
analgesic  An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
ChEBI Ontology
Outgoing Relation(s)
GW405833 (CHEBI:92184) has role analgesic (CHEBI:35480)
GW405833 (CHEBI:92184) has role anti-inflammatory agent (CHEBI:67079)
GW405833 (CHEBI:92184) has role CB2 receptor agonist (CHEBI:146246)
GW405833 (CHEBI:92184) is a N-acylindole (CHEBI:75884)
GW405833 (CHEBI:92184) is a aromatic ether (CHEBI:35618)
GW405833 (CHEBI:92184) is a benzamides (CHEBI:22702)
GW405833 (CHEBI:92184) is a dichlorobenzene (CHEBI:23697)
GW405833 (CHEBI:92184) is a methylindole (CHEBI:38460)
GW405833 (CHEBI:92184) is a morpholines (CHEBI:38785)
IUPAC Name 
(2,3-dichlorophenyl){5-methoxy-2-methyl-3-[2-(morpholin-4-yl)ethyl]-1H-indol-1-yl}methanone
Synonyms  Source
(2,3-dichlorophenyl)-[5-methoxy-2-methyl-3-[2-(4-morpholinyl)ethyl]-1-indolyl]methanoneChEBI
(2,3-dichlorophenyl)[5-methoxy-2-methyl-3-[2-(4-morpholinyl)ethyl]-1H-indol-1-yl]methanoneChEBI
L768242ChEBI
L 768242ChEBI
L-768242ChEBI
GW 405833ChEBI
Manual XrefsDatabases
LSM-2217LINCS
GW-405,833Wikipedia
Registry NumbersSources
CAS:180002-83-9ChEBI
Citations