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CHEBI:91107 - SB 415286

ChEBI IDCHEBI:91107
ChEBI NameSB 415286
Stars
DefinitionA member of the class of maleimides carrying 3-chloro-4-hydroxyphenylamino and 2-nitrophenyl substituents at positions 3 and 4 respectively.
Last Modified23 January 2023
SubmitterSteve
DownloadsMolfile
FormulaC16H10ClN3O5
Net Charge0
Average Mass359.725
Monoisotopic Mass359.03090
SMILESO=C1NC(=O)C(c2ccccc2[N+](=O)[O-])=C1Nc1ccc(O)c(Cl)c1
InChIInChI=1S/C16H10ClN3O5/c17-10-7-8(5-6-12(10)21)18-14-13(15(22)19-16(14)23)9-3-1-2-4-11(9)20(24)25/h1-7,21H,(H2,18,19,22,23)
InChIKeyPQCXVIPXISBFPN-UHFFFAOYSA-N
Roles Classification
Chemical Roles:
antioxidant  A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
EC 2.7.11.26 (tau-protein kinase) inhibitor  An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of tau-protein kinase inhibitor (EC 2.7.11.26).
apoptosis inducer  Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
Application:
neuroprotective agent  Any compound that can be used for the treatment of neurodegenerative disorders.
ChEBI Ontology
Outgoing Relation(s)
SB 415286 (CHEBI:91107) has role antioxidant (CHEBI:22586)
SB 415286 (CHEBI:91107) has role apoptosis inducer (CHEBI:68495)
SB 415286 (CHEBI:91107) has role EC 2.7.11.26 (tau-protein kinase) inhibitor (CHEBI:91092)
SB 415286 (CHEBI:91107) has role neuroprotective agent (CHEBI:63726)
SB 415286 (CHEBI:91107) is a C-nitro compound (CHEBI:35716)
SB 415286 (CHEBI:91107) is a maleimides (CHEBI:55417)
SB 415286 (CHEBI:91107) is a monochlorobenzenes (CHEBI:83403)
SB 415286 (CHEBI:91107) is a phenols (CHEBI:33853)
SB 415286 (CHEBI:91107) is a secondary amino compound (CHEBI:50995)
SB 415286 (CHEBI:91107) is a substituted aniline (CHEBI:48975)
IUPAC Name 
3-(3-chloro-4-hydroxyanilino)-4-(2-nitrophenyl)-1H-pyrrole-2,5-dione
Synonyms  Source
SB-415286ChemIDplus
3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dioneChemIDplus
SB415286ChEBI
Manual XrefsDatabases
LSM-3719LINCS
Registry NumbersSources
Reaxys:8795652Reaxys
CAS:264218-23-7ChemIDplus
Citations