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CHEBI:90724 - AM-251
| Formula | C22H21Cl2IN4O |
| Net Charge | 0 |
| Average Mass | 555.247 |
| Monoisotopic Mass | 554.01371 |
| SMILES | Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(I)cc1 |
| InChI | InChI=1S/C22H21Cl2IN4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(25)9-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30) |
| InChIKey | BUZAJRPLUGXRAB-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Roles Classification |
|---|
| Biological Roles: | CB1 receptor antagonist An antagonist that binds to and deactivates type 1 cannabinoid receptors. apoptosis inducer Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms. |
| Applications: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| AM-251 (CHEBI:90724) has role antidepressant (CHEBI:35469) |
| AM-251 (CHEBI:90724) has role antineoplastic agent (CHEBI:35610) |
| AM-251 (CHEBI:90724) has role apoptosis inducer (CHEBI:68495) |
| AM-251 (CHEBI:90724) has role CB1 receptor antagonist (CHEBI:73416) |
| AM-251 (CHEBI:90724) is a amidopiperidine (CHEBI:48613) |
| AM-251 (CHEBI:90724) is a carbohydrazide (CHEBI:35363) |
| AM-251 (CHEBI:90724) is a dichlorobenzene (CHEBI:23697) |
| AM-251 (CHEBI:90724) is a organoiodine compound (CHEBI:37142) |
| AM-251 (CHEBI:90724) is a pyrazoles (CHEBI:26410) |
| IUPAC Name |
|---|
| 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide |
| Synonyms | Source |
|---|---|
| AM251 | KEGG COMPOUND |
| AM 251 | KEGG COMPOUND |
| Registry Numbers | Sources |
|---|---|
| Reaxys:7780333 | Reaxys |
| CAS:183232-66-8 | KEGG COMPOUND |
| CAS:183232-66-8 | ChemIDplus |
| Citations |
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