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CHEBI:8863 - Riluzole
| Formula | C8H5F3N2OS |
| Net Charge | 0 |
| Average Mass | 234.202 |
| Monoisotopic Mass | 234.00747 |
| SMILES | Nc1nc2ccc(OC(F)(F)F)cc2s1 |
| InChI | InChI=1S/C8H5F3N2OS/c9-8(10,11)14-4-1-2-5-6(3-4)15-7(12)13-5/h1-3H,(H2,12,13) |
| InChIKey | FTALBRSUTCGOEG-UHFFFAOYSA-N |
| Roles Classification |
|---|
| Biological Role: | immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. |
| Applications: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. anti-arrhythmia drug A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| Riluzole (CHEBI:8863) has role anti-arrhythmia drug (CHEBI:38070) |
| Riluzole (CHEBI:8863) has role antidepressant (CHEBI:35469) |
| Riluzole (CHEBI:8863) has role antineoplastic agent (CHEBI:35610) |
| Riluzole (CHEBI:8863) has role antipsychotic agent (CHEBI:35476) |
| Riluzole (CHEBI:8863) has role immunosuppressive agent (CHEBI:35705) |
| Riluzole (CHEBI:8863) is a benzothiazoles (CHEBI:37947) |
| INN | Source |
|---|---|
| riluzol | WHO MedNet |
| Synonyms | Source |
|---|---|
| 6-Trifluoromethoxybenzothiazol-2-ylamine | DrugCentral |
| BHV-0223 | ChEMBL |
| NSC-753433 | ChEMBL |
| NSC-759823 | ChEMBL |
| rilutek | DrugCentral |
| rilutor | DrugCentral |
| Brand Names | Source |
|---|---|
| Exservan | ChEMBL |
| Riluzole zentiva | ChEMBL |
| Teglutik | ChEMBL |
| Tiglutik kit | ChEMBL |
| Manual Xrefs | Databases |
|---|---|
| 2382 | DrugCentral |
| C07937 | KEGG COMPOUND |
| D00775 | KEGG DRUG |
| HMDB0014878 | HMDB |
| LSM-2471 | LINCS |
| Registry Numbers | Sources |
|---|---|
| CAS:1744-22-5 | KEGG COMPOUND |
| Citations |
|---|