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CHEBI:88301 - azaperone

Default Structure
ChEBI IDCHEBI:88301
ChEBI Nameazaperone
Stars
DefinitionAn N-arylpiperazine that is 2-(piperazin-1-yl)pyridine in which the amino hydrogen is replaced by a 3-(4-fluobenzoyl)propyl group. Used mainly as a tranquiliser for pigs and elephants.
Last Modified25 February 2016
SubmitterSteve
DownloadsMolfile
FormulaC19H22FN3O
Net Charge0
Average Mass327.403
Monoisotopic Mass327.17469
SMILESO=C(CCCN1CCN(c2ccccn2)CC1)c1ccc(F)cc1
InChIInChI=1S/C19H22FN3O/c20-17-8-6-16(7-9-17)18(24)4-3-11-22-12-14-23(15-13-22)19-5-1-2-10-21-19/h1-2,5-10H,3-4,11-15H2
InChIKeyXTKDAFGWCDAMPY-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Role:
dopaminergic antagonist  A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
Applications:
dopaminergic antagonist  A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
antipsychotic agent  Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
ChEBI Ontology
Outgoing Relation(s)
azaperone (CHEBI:88301) has role antipsychotic agent (CHEBI:35476)
azaperone (CHEBI:88301) has role dopaminergic antagonist (CHEBI:48561)
azaperone (CHEBI:88301) is a N-alkylpiperazine (CHEBI:46845)
azaperone (CHEBI:88301) is a N-arylpiperazine (CHEBI:46848)
azaperone (CHEBI:88301) is a aminopyridine (CHEBI:38207)
azaperone (CHEBI:88301) is a aromatic ketone (CHEBI:76224)
azaperone (CHEBI:88301) is a monofluorobenzenes (CHEBI:83575)
azaperone (CHEBI:88301) is a tertiary amino compound (CHEBI:50996)
IUPAC Name 
1-(4-fluorophenyl)-4-[4-(pyridin-2-yl)piperazin-1-yl]butan-1-one
INNs  Source
azaperonaChemIDplus
azaperoneKEGG DRUG
azaperoneChemIDplus
azaperonumChemIDplus
Synonyms  Source
1-(3-(4-Fluorobenzoyl)propyl)-4-(2-pyridyl)piperazineChemIDplus
1-(4-Fluorophenyl)-4-[4-(2-pyridinyl)-1-piperazinyl]-1-butanoneNIST Chemistry WebBook
4'-Fluoro-4-(4-(2-pyridyl)-1-piperazinyl)butyrophenoneChemIDplus
AzaperonChemIDplus
NSC 170976NIST Chemistry WebBook
Brand Name  Source
StresnilKEGG DRUG
Manual XrefsDatabases
1871VSDB
AzaperoneWikipedia
D02620KEGG DRUG
LSM-3012LINCS
Registry NumbersSources
Reaxys:565491Reaxys
CAS:1649-18-9KEGG DRUG
CAS:1649-18-9ChemIDplus
CAS:1649-18-9NIST Chemistry WebBook
Citations