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CHEBI:8764 - mycophenolate mofetil
| Formula | C23H31NO7 |
| Net Charge | 0 |
| Average Mass | 433.501 |
| Monoisotopic Mass | 433.21005 |
| SMILES | COc1c(C)c2c(c(O)c1C/C=C(\C)CCC(=O)OCCN1CCOCC1)C(=O)OC2 |
| InChI | InChI=1S/C23H31NO7/c1-15(5-7-19(25)30-13-10-24-8-11-29-12-9-24)4-6-17-21(26)20-18(14-31-23(20)27)16(2)22(17)28-3/h4,26H,5-14H2,1-3H3/b15-4+ |
| InChIKey | RTGDFNSFWBGLEC-SYZQJQIISA-N |
| Wikipedia |
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| Roles Classification |
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| Chemical Role: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | EC 1.1.1.205 (IMP dehydrogenase) inhibitor An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD+ or NADP+ acceptor) inhibitor that interferes with the action of IMP dehydrogenase (EC 1.1.1.205), so blocking de novo biosynthesis of purine nucleotides. antiviral agent A substance that destroys or inhibits replication of viruses. antithyroid drug A drug used to treat hyperthyroidism by reducing the excessive production of thyroid hormones. anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. anticoronaviral agent Any antiviral agent which inhibits the activity of coronaviruses. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. |
| Applications: | prodrug A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug. antithyroid drug A drug used to treat hyperthyroidism by reducing the excessive production of thyroid hormones. hypoglycemic agent A drug which lowers the blood glucose level. gout suppressant A drug that increases uric acid excretion by the kidney (uricosuric drug), decreases uric acid production (antihyperuricemic), or alleviates the pain and inflammation of acute attacks of gout. nephroprotective agent Any protective agent that is able to prevent damage to the kidney. anti-inflammatory agent Any compound that has anti-inflammatory effects. antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. anti-anaemic agent A compound which increases either the number of red cells or the amount of haemoglobin in the blood. antirheumatic drug A drug used to treat rheumatoid arthritis. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. renoprotective agent Any compound that is able to prevent damage to the kidneys. antipsoriatic A drug used to treat psoriasis. ophthalmology drug Any compound used for the treatment of eye conditions or eye diseases. antifibrotic agent Any agent which acts to reduce fibrosis. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| mycophenolate mofetil (CHEBI:8764) has functional parent 2-(morpholin-4-yl)ethanol (CHEBI:67144) |
| mycophenolate mofetil (CHEBI:8764) has functional parent mycophenolic acid (CHEBI:168396) |
| mycophenolate mofetil (CHEBI:8764) has role anti-anaemic agent (CHEBI:75835) |
| mycophenolate mofetil (CHEBI:8764) has role anti-HIV agent (CHEBI:64946) |
| mycophenolate mofetil (CHEBI:8764) has role anti-inflammatory agent (CHEBI:67079) |
| mycophenolate mofetil (CHEBI:8764) has role anticoronaviral agent (CHEBI:149553) |
| mycophenolate mofetil (CHEBI:8764) has role antifibrotic agent (CHEBI:233423) |
| mycophenolate mofetil (CHEBI:8764) has role antihypertensive agent (CHEBI:35674) |
| mycophenolate mofetil (CHEBI:8764) has role antineoplastic agent (CHEBI:35610) |
| mycophenolate mofetil (CHEBI:8764) has role antipsoriatic (CHEBI:50748) |
| mycophenolate mofetil (CHEBI:8764) has role antirheumatic drug (CHEBI:35842) |
| mycophenolate mofetil (CHEBI:8764) has role antithyroid drug (CHEBI:50671) |
| mycophenolate mofetil (CHEBI:8764) has role antiviral agent (CHEBI:22587) |
| mycophenolate mofetil (CHEBI:8764) has role cardiovascular drug (CHEBI:35554) |
| mycophenolate mofetil (CHEBI:8764) has role EC 1.1.1.205 (IMP dehydrogenase) inhibitor (CHEBI:53746) |
| mycophenolate mofetil (CHEBI:8764) has role gout suppressant (CHEBI:35845) |
| mycophenolate mofetil (CHEBI:8764) has role hypoglycemic agent (CHEBI:35526) |
| mycophenolate mofetil (CHEBI:8764) has role immunosuppressive agent (CHEBI:35705) |
| mycophenolate mofetil (CHEBI:8764) has role nephroprotective agent (CHEBI:76595) |
| mycophenolate mofetil (CHEBI:8764) has role ophthalmology drug (CHEBI:66981) |
| mycophenolate mofetil (CHEBI:8764) has role prodrug (CHEBI:50266) |
| mycophenolate mofetil (CHEBI:8764) has role renoprotective agent (CHEBI:231911) |
| mycophenolate mofetil (CHEBI:8764) is a carboxylic ester (CHEBI:33308) |
| mycophenolate mofetil (CHEBI:8764) is a ether (CHEBI:25698) |
| mycophenolate mofetil (CHEBI:8764) is a phenols (CHEBI:33853) |
| mycophenolate mofetil (CHEBI:8764) is a tertiary amino compound (CHEBI:50996) |
| mycophenolate mofetil (CHEBI:8764) is a γ-lactone (CHEBI:37581) |
| IUPAC Name |
|---|
| 2-(morpholin-4-yl)ethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoate |
| Synonyms | Source |
|---|---|
| 2-morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate | ChemIDplus |
| MMF | ChEBI |
| Mycophenolic acid 2-(4-morpholinyl)ethyl ester | ChEMBL |
| mycophenolic acid morpholinoethyl ester | ChemIDplus |
| Mycophenylate mofetil | ChEMBL |
| Myhibbin | ChEMBL |
| Brand Names | Source |
|---|---|
| Arzip | ChEMBL |
| Cellcept | KEGG DRUG |
| Mycophenolate mofetil teva | ChEMBL |
| UniProt Name | Source |
|---|---|
| mycophenolate mofetil | UniProt |
| Manual Xrefs | Databases |
|---|---|
| 1859 | DrugCentral |
| C07908 | KEGG COMPOUND |
| D00752 | KEGG DRUG |
| DB00688 | DrugBank |
| HMDB0014826 | HMDB |
| Mycophenolate_mofetil | Wikipedia |
| Registry Numbers | Sources |
|---|---|
| Reaxys:7500599 | Reaxys |
| CAS:128794-94-5 | KEGG COMPOUND |
| CAS:128794-94-5 | ChemIDplus |
| Citations |
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