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CHEBI:86989 - stattic

ChEBI IDCHEBI:86989
ChEBI Namestattic
Stars
DefinitionA member of the class of 1-benzothiophenes that is 1-benzothiophene-1,1-dioxide substituted at position 6 by a nitro group. Used as a radiosensitising agent for esophageal squamous cell carcinoma.
Last Modified11 August 2016
SubmitterTheOtherDave
DownloadsMolfile
FormulaC8H5NO4S
Net Charge0
Average Mass211.198
Monoisotopic Mass210.99393
SMILESO=[N+]([O-])c1ccc2c(c1)S(=O)(=O)C=C2
InChIInChI=1S/C8H5NO4S/c10-9(11)7-2-1-6-3-4-14(12,13)8(6)5-7/h1-5H
InChIKeyZRRGOUHITGRLBA-UHFFFAOYSA-N
Roles Classification
Biological Role:
STAT3 inhibitor  An inhibitor of signal transducer and activator of transcription 3 (STAT3)
Applications:
radiosensitizing agent  A drug that makes increases the sensitivity of tumour cells to radiation therapy.
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
stattic (CHEBI:86989) has role antineoplastic agent (CHEBI:35610)
stattic (CHEBI:86989) has role radiosensitizing agent (CHEBI:132992)
stattic (CHEBI:86989) has role STAT3 inhibitor (CHEBI:87183)
stattic (CHEBI:86989) is a C-nitro compound (CHEBI:35716)
stattic (CHEBI:86989) is a 1-benzothiophenes (CHEBI:38836)
stattic (CHEBI:86989) is a sulfone (CHEBI:35850)
IUPAC Name 
6-nitro-1H-1-benzothiophene-1,1-dione
Synonyms  Source
6-nitro-1-benzothiophene 1,1-dioxideSUBMITTER
CHEMBL1337170SUBMITTER
STAT3 Inhibitor VSUBMITTER
Registry NumbersSources
Reaxys:11410Reaxys
Citations