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CHEBI:86289 - DMH1

ChEBI IDCHEBI:86289
ChEBI NameDMH1
Stars
DefinitionA pyrazolopyrimidine that is pyrazolo[1,5-a]pyrimidine bearing quinolin-4-yl and 4-isopropyloxyphenyl substituents at positions 3 and 6 respectively.
Last Modified6 July 2016
SubmitterCeri
DownloadsMolfile
FormulaC24H20N4O
Net Charge0
Average Mass380.451
Monoisotopic Mass380.16371
SMILESCC(C)Oc1ccc(-c2cnc3c(-c4ccnc5ccccc45)cnn3c2)cc1
InChIInChI=1S/C24H20N4O/c1-16(2)29-19-9-7-17(8-10-19)18-13-26-24-22(14-27-28(24)15-18)20-11-12-25-23-6-4-3-5-21(20)23/h3-16H,1-2H3
InChIKeyJMIFGARJSWXZSH-UHFFFAOYSA-N
Roles Classification
Biological Roles:
bone morphogenetic protein receptor antagonist  An antagonist at the bone morphogenetic protein receptor.
protein kinase inhibitor  An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of protein kinases.
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
DMH1 (CHEBI:86289) has role antineoplastic agent (CHEBI:35610)
DMH1 (CHEBI:86289) has role bone morphogenetic protein receptor antagonist (CHEBI:78623)
DMH1 (CHEBI:86289) has role protein kinase inhibitor (CHEBI:37699)
DMH1 (CHEBI:86289) is a aromatic ether (CHEBI:35618)
DMH1 (CHEBI:86289) is a pyrazolopyrimidine (CHEBI:38669)
DMH1 (CHEBI:86289) is a quinolines (CHEBI:26513)
IUPAC Name 
4-(6-{4-[(propan-2-yl)oxy]phenyl}pyrazolo[1,5-a]pyrimidin-3-yl)quinoline
Synonyms  Source
DMH-1ChEBI
DMH 1ChEBI
Registry NumbersSources
Reaxys:20934957Reaxys
Citations