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CHEBI:8466 - propafenone hydrochloride

ChEBI IDCHEBI:8466
ChEBI Namepropafenone hydrochloride
Stars
DefinitionA hydrochloride that is the monohydrochloride salt of propafenone. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used in the management of supraventricular and ventricular arrhythmias.
Last Modified19 January 2012
DownloadsMolfile
FormulaC21H27NO3.HCl
Net Charge0
Average Mass377.912
Monoisotopic Mass377.17577
SMILESCCCNCC(O)COc1ccccc1C(=O)CCc1ccccc1.Cl
InChIInChI=1S/C21H27NO3.ClH/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17;/h3-11,18,22-23H,2,12-16H2,1H3;1H
InChIKeyXWIHRGFIPXWGEF-UHFFFAOYSA-N
Roles Classification
Application:
anti-arrhythmia drug  A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
ChEBI Ontology
Outgoing Relation(s)
propafenone hydrochloride (CHEBI:8466) has part propafenone(1+) (CHEBI:63650)
propafenone hydrochloride (CHEBI:8466) has role anti-arrhythmia drug (CHEBI:38070)
propafenone hydrochloride (CHEBI:8466) is a hydrochloride (CHEBI:36807)
IUPAC Name 
1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one hydrochloride
Synonyms  Source
propafenone HClChemIDplus
Propafenon hydrochloridChemIDplus
2-hydroxy-3-[2-(3-phenylpropanoyl)phenoxy]-N-propylpropan-1-aminium chlorideIUPAC
Brand Names  Source
RythmolKEGG DRUG
ArythmolChEBI
Manual XrefsDatabases
D00640KEGG DRUG
DB01182DrugBank
Registry NumbersSources
Reaxys:4343069Reaxys
CAS:34183-22-7ChemIDplus
CAS:34183-22-7KEGG DRUG