CHEBI:8448 - procyclidine

ChEBI IDCHEBI:8448
ChEBI Nameprocyclidine
Stars
DefinitionA tertiary alcohol that consists of propan-1-ol substituted by a cyclohexyl and a phenyl group at position 1 and a pyrrolidin-1-yl group at position 3.
Last Modified22 February 2017
DownloadsMolfile
FormulaC19H29NO
Net Charge0
Average Mass287.447
Monoisotopic Mass287.22491
SMILESOC(CCN1CCCC1)(c1ccccc1)C1CCCCC1
InChIInChI=1S/C19H29NO/c21-19(17-9-3-1-4-10-17,18-11-5-2-6-12-18)13-16-20-14-7-8-15-20/h1,3-4,9-10,18,21H,2,5-8,11-16H2
InChIKeyWYDUSKDSKCASEF-UHFFFAOYSA-N
Roles Classification
Biological Role:
muscarinic antagonist  A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
Applications:
antidyskinesia agent  Any compound which can be used to treat or alleviate the symptoms of dyskinesia.
antiparkinson drug  A drug used in the treatment of Parkinson's disease.
muscarinic antagonist  A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
ChEBI Ontology
Outgoing Relation(s)
procyclidine (CHEBI:8448) has role antidyskinesia agent (CHEBI:66956)
procyclidine (CHEBI:8448) has role antiparkinson drug (CHEBI:48407)
procyclidine (CHEBI:8448) has role muscarinic antagonist (CHEBI:48876)
procyclidine (CHEBI:8448) is a pyrrolidines (CHEBI:38260)
procyclidine (CHEBI:8448) is a tertiary alcohol (CHEBI:26878)
Incoming Relation(s)
procyclidine hydrochloride (CHEBI:8449) has part procyclidine (CHEBI:8448)
IUPAC Name 
1-cyclohexyl-1-phenyl-3-(pyrrolidin-1-yl)propan-1-ol
INNs  Source
procyclidineChemIDplus
procyclidinumWHO MedNet
procyclidineWHO MedNet
prociclidinaWHO MedNet
Synonyms  Source
ProcyclidineKEGG COMPOUND
1-Cyclohexyl-1-phenyl-3-pyrrolidino-1-propanolChemIDplus
TricyclamolChemIDplus
Manual XrefsDatabases
C07378KEGG COMPOUND
DB00387DrugBank
US2891890Patent
US2826590Patent
HMDB0014531HMDB
D08425KEGG DRUG
LSM-4396LINCS
2276DrugCentral
Registry NumbersSources
Reaxys:88563Reaxys
CAS:77-37-2KEGG COMPOUND
CAS:77-37-2ChemIDplus
Citations