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CHEBI:8426 - probenecid
| Formula | C13H19NO4S |
| Net Charge | 0 |
| Average Mass | 285.365 |
| Monoisotopic Mass | 285.10348 |
| SMILES | CCCN(CCC)S(=O)(=O)c1ccc(C(=O)O)cc1 |
| InChI | InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16) |
| InChIKey | DBABZHXKTCFAPX-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Roles Classification |
|---|
| Chemical Role: | Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Brønsted base). |
| Biological Roles: | antiviral agent A substance that destroys or inhibits replication of viruses. antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria. anti-obesity agent Any substance which is used to reduce or control weight. |
| Applications: | neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders. gout suppressant A drug that increases uric acid excretion by the kidney (uricosuric drug), decreases uric acid production (antihyperuricemic), or alleviates the pain and inflammation of acute attacks of gout. hypoglycemic agent A drug which lowers the blood glucose level. uricosuric drug A gout suppressant that acts directly on the renal tubule to increase the excretion of uric acid, thus reducing its concentrations in plasma. antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases. renoprotective agent Any compound that is able to prevent damage to the kidneys. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| probenecid (CHEBI:8426) has role anti-obesity agent (CHEBI:74518) |
| probenecid (CHEBI:8426) has role antibacterial agent (CHEBI:33282) |
| probenecid (CHEBI:8426) has role antiinfective agent (CHEBI:35441) |
| probenecid (CHEBI:8426) has role antineoplastic agent (CHEBI:35610) |
| probenecid (CHEBI:8426) has role antiviral agent (CHEBI:22587) |
| probenecid (CHEBI:8426) has role cardiovascular drug (CHEBI:35554) |
| probenecid (CHEBI:8426) has role gout suppressant (CHEBI:35845) |
| probenecid (CHEBI:8426) has role hypoglycemic agent (CHEBI:35526) |
| probenecid (CHEBI:8426) has role neuroprotective agent (CHEBI:63726) |
| probenecid (CHEBI:8426) has role renoprotective agent (CHEBI:231911) |
| probenecid (CHEBI:8426) has role uricosuric drug (CHEBI:35841) |
| probenecid (CHEBI:8426) is a benzoic acids (CHEBI:22723) |
| probenecid (CHEBI:8426) is a sulfonamide (CHEBI:35358) |
| IUPAC Name |
|---|
| 4-(dipropylsulfamoyl)benzoic acid |
| INNs | Source |
|---|---|
| probenecid | ChemIDplus |
| probenecida | ChemIDplus |
| probenecide | ChemIDplus |
| probenecidum | ChemIDplus |
| Synonyms | Source |
|---|---|
| 4-(Di-n-propylsulfamoyl)benzoesäure | ChemIDplus |
| 4-((Dipropylamino)sulfonyl)benzoic acid | ChemIDplus |
| 4-(N,N-Dipropylsulfamoyl)benzoesäure | ChemIDplus |
| HC 5006 | ChEMBL |
| NSC-18786 | ChEMBL |
| p-(Dipropylsulfamoyl)benzoic acid | ChemIDplus |
| Brand Names | Source |
|---|---|
| Benemid | ChEMBL |
| Benuryl | ChEMBL |
| Probalan | ChEMBL |
| Probampicin | ChEMBL |
| Probenecid component of col- | ChEMBL |
| Probenecid component of colbenemid | ChEMBL |
| Citations |
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