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CHEBI:8382 - prednisone
| Formula | C21H26O5 |
| Net Charge | 0 |
| Average Mass | 358.434 |
| Monoisotopic Mass | 358.17802 |
| SMILES | [H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)CC(=O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@@]21C |
| InChI | InChI=1S/C21H26O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,18,22,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1 |
| InChIKey | XOFYZVNMUHMLCC-ZPOLXVRWSA-N |
| Wikipedia |
|---|
| Roles Classification |
|---|
| Biological Roles: | anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. adrenergic agent Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. antiviral agent A substance that destroys or inhibits replication of viruses. hormone Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds. |
| Applications: | anti-allergic agent A drug used to treat allergic reactions. antifibrotic agent Any agent which acts to reduce fibrosis. ophthalmology drug Any compound used for the treatment of eye conditions or eye diseases. antipsoriatic A drug used to treat psoriasis. adrenergic agent Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter. dermatologic drug A drug used to treat or prevent skin disorders or for the routine care of skin. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. anti-inflammatory drug A substance that reduces or suppresses inflammation. renoprotective agent Any compound that is able to prevent damage to the kidneys. nephroprotective agent Any protective agent that is able to prevent damage to the kidney. anti-anaemic agent A compound which increases either the number of red cells or the amount of haemoglobin in the blood. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. antirheumatic drug A drug used to treat rheumatoid arthritis. hypoglycemic agent A drug which lowers the blood glucose level. anti-ulcer drug One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract. antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. anti-inflammatory agent Any compound that has anti-inflammatory effects. anti-asthmatic agent Any compound that has anti-asthmatic effects. prodrug A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug. cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| prednisone (CHEBI:8382) has role adrenergic agent (CHEBI:37962) |
| prednisone (CHEBI:8382) has role analgesic (CHEBI:35480) |
| prednisone (CHEBI:8382) has role anti-allergic agent (CHEBI:50857) |
| prednisone (CHEBI:8382) has role anti-anaemic agent (CHEBI:75835) |
| prednisone (CHEBI:8382) has role anti-asthmatic agent (CHEBI:65023) |
| prednisone (CHEBI:8382) has role anti-HIV agent (CHEBI:64946) |
| prednisone (CHEBI:8382) has role anti-inflammatory agent (CHEBI:67079) |
| prednisone (CHEBI:8382) has role anti-inflammatory drug (CHEBI:35472) |
| prednisone (CHEBI:8382) has role anti-ulcer drug (CHEBI:49201) |
| prednisone (CHEBI:8382) has role antifibrotic agent (CHEBI:233423) |
| prednisone (CHEBI:8382) has role antimicrobial agent (CHEBI:33281) |
| prednisone (CHEBI:8382) has role antineoplastic agent (CHEBI:35610) |
| prednisone (CHEBI:8382) has role antipsoriatic (CHEBI:50748) |
| prednisone (CHEBI:8382) has role antirheumatic drug (CHEBI:35842) |
| prednisone (CHEBI:8382) has role antitubercular agent (CHEBI:33231) |
| prednisone (CHEBI:8382) has role antiviral agent (CHEBI:22587) |
| prednisone (CHEBI:8382) has role cardiovascular drug (CHEBI:35554) |
| prednisone (CHEBI:8382) has role dermatologic drug (CHEBI:50177) |
| prednisone (CHEBI:8382) has role hypoglycemic agent (CHEBI:35526) |
| prednisone (CHEBI:8382) has role immunosuppressive agent (CHEBI:35705) |
| prednisone (CHEBI:8382) has role nephroprotective agent (CHEBI:76595) |
| prednisone (CHEBI:8382) has role ophthalmology drug (CHEBI:66981) |
| prednisone (CHEBI:8382) has role prodrug (CHEBI:50266) |
| prednisone (CHEBI:8382) has role renoprotective agent (CHEBI:231911) |
| prednisone (CHEBI:8382) is a 11-oxo steroid (CHEBI:47787) |
| prednisone (CHEBI:8382) is a 17α-hydroxy steroid (CHEBI:35342) |
| prednisone (CHEBI:8382) is a 20-oxo steroid (CHEBI:36885) |
| prednisone (CHEBI:8382) is a 21-hydroxy steroid (CHEBI:35344) |
| prednisone (CHEBI:8382) is a 3-oxo-Δ1,Δ4-steroid (CHEBI:77166) |
| prednisone (CHEBI:8382) is a C21-steroid (CHEBI:61313) |
| prednisone (CHEBI:8382) is a glucocorticoid (CHEBI:24261) |
| prednisone (CHEBI:8382) is a primary α-hydroxy ketone (CHEBI:139590) |
| prednisone (CHEBI:8382) is a tertiary α-hydroxy ketone (CHEBI:139592) |
| Incoming Relation(s) |
| 20α-dihydroprednisone (CHEBI:182969) has functional parent prednisone (CHEBI:8382) |
| 20β-dihydroprednisone (CHEBI:182970) has functional parent prednisone (CHEBI:8382) |
| 6α-hydroxyprednisone (CHEBI:180929) has functional parent prednisone (CHEBI:8382) |
| 6β-hydroxyprednisone (CHEBI:180930) has functional parent prednisone (CHEBI:8382) |
| cortancyl (CHEBI:34655) has functional parent prednisone (CHEBI:8382) |
| Δ6-prednisone (CHEBI:180928) has functional parent prednisone (CHEBI:8382) |
| IUPAC Name |
|---|
| 17,21-dihydroxypregna-1,4-diene-3,11,20-trione |
| INNs | Source |
|---|---|
| prednisona | ChemIDplus |
| prednisone | ChEBI |
| prednisone | ChemIDplus |
| prednisonum | ChemIDplus |
| Synonyms | Source |
|---|---|
| 1,2-Dehydrocortisone | ChemIDplus |
| 1,4-Pregnadiene-17α,21-diol-3,11,20-trione | ChemIDplus |
| 17,21-Dihydroxypregna-1,4-diene-3,11,20-trione | ChemIDplus |
| 3en3hg4wsw | ChEMBL |
| Decortin | ChEMBL |
| Dehydrocortisone | ChEBI |
| Brand Names | Source |
|---|---|
| Cortan | ChEMBL |
| Decortisyl | ChEMBL |
| Delta-dome | ChEMBL |
| Deltasone | ChEMBL |
| Fernisone | ChEMBL |
| Liquid pred | ChEMBL |
| UniProt Name | Source |
|---|---|
| prednisone | UniProt |
| Citations |
|---|