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CHEBI:8382 - prednisone
| Formula | C21H26O5 |
| Net Charge | 0 |
| Average Mass | 358.434 |
| Monoisotopic Mass | 358.17802 |
| SMILES | [H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)CC(=O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@@]21C |
| InChI | InChI=1S/C21H26O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,18,22,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1 |
| InChIKey | XOFYZVNMUHMLCC-ZPOLXVRWSA-N |
| Wikipedia |
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| Roles Classification |
|---|
| Biological Roles: | adrenergic agent Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. hormone Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds. |
| Applications: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. adrenergic agent Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter. anti-inflammatory drug A substance that reduces or suppresses inflammation. prodrug A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| prednisone (CHEBI:8382) has role adrenergic agent (CHEBI:37962) |
| prednisone (CHEBI:8382) has role anti-inflammatory drug (CHEBI:35472) |
| prednisone (CHEBI:8382) has role antineoplastic agent (CHEBI:35610) |
| prednisone (CHEBI:8382) has role immunosuppressive agent (CHEBI:35705) |
| prednisone (CHEBI:8382) has role prodrug (CHEBI:50266) |
| prednisone (CHEBI:8382) is a 11-oxo steroid (CHEBI:47787) |
| prednisone (CHEBI:8382) is a 17α-hydroxy steroid (CHEBI:35342) |
| prednisone (CHEBI:8382) is a 20-oxo steroid (CHEBI:36885) |
| prednisone (CHEBI:8382) is a 21-hydroxy steroid (CHEBI:35344) |
| prednisone (CHEBI:8382) is a 3-oxo-Δ1,Δ4-steroid (CHEBI:77166) |
| prednisone (CHEBI:8382) is a C21-steroid (CHEBI:61313) |
| prednisone (CHEBI:8382) is a glucocorticoid (CHEBI:24261) |
| prednisone (CHEBI:8382) is a primary α-hydroxy ketone (CHEBI:139590) |
| prednisone (CHEBI:8382) is a tertiary α-hydroxy ketone (CHEBI:139592) |
| Incoming Relation(s) |
| 20α-dihydroprednisone (CHEBI:182969) has functional parent prednisone (CHEBI:8382) |
| 20β-dihydroprednisone (CHEBI:182970) has functional parent prednisone (CHEBI:8382) |
| 6α-hydroxyprednisone (CHEBI:180929) has functional parent prednisone (CHEBI:8382) |
| 6β-hydroxyprednisone (CHEBI:180930) has functional parent prednisone (CHEBI:8382) |
| cortancyl (CHEBI:34655) has functional parent prednisone (CHEBI:8382) |
| Δ6-prednisone (CHEBI:180928) has functional parent prednisone (CHEBI:8382) |
| IUPAC Name |
|---|
| 17,21-dihydroxypregna-1,4-diene-3,11,20-trione |
| INNs | Source |
|---|---|
| prednisone | ChEBI |
| prednisona | ChemIDplus |
| prednisonum | ChemIDplus |
| prednisone | ChemIDplus |
| Synonyms | Source |
|---|---|
| 1,2-Dehydrocortisone | ChemIDplus |
| 1,4-Pregnadiene-17α,21-diol-3,11,20-trione | ChemIDplus |
| 17,21-Dihydroxypregna-1,4-diene-3,11,20-trione | ChemIDplus |
| Dehydrocortisone | ChEBI |
| prednison | ChEBI |
| Citations |
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