prednisolone sodium phosphate (CHEBI:8379)

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CHEBI:8379 - prednisolone sodium phosphate

ChEBI ID	CHEBI:8379
ChEBI Name	prednisolone sodium phosphate
Stars
Definition	An organic sodium salt of prednisolone phosphate. It is an ophthalmology drug used for the treatment of short-term inflammatory eye conditions and helps relieve inflammation, redness and irritation of the eyes.
Last Modified	19 December 2019
Downloads	Molfile

Formula	C21H27O8P.2Na
Net Charge	0
Average Mass	484.393
Monoisotopic Mass	484.12389
SMILES	[H][C@@]12CC[C@](O)(C(=O)COP(=O)([O-])[O-])[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@@]21C.[Na+].[Na+]
InChI	InChI=1S/C21H29O8P.2Na/c1-19-7-5-13(22)9-12(19)3-4-14-15-6-8-21(25,17(24)11-29-30(26,27)28)20(15,2)10-16(23)18(14)19;;/h5,7,9,14-16,18,23,25H,3-4,6,8,10-11H2,1-2H3,(H2,26,27,28);;/q;2*+1/p-2/t14-,15-,16-,18+,19-,20-,21-;;/m0../s1
InChIKey	VJZLQIPZNBPASX-OJJGEMKLSA-L

Wikipedia

Roles Classification

Biological Roles:

glucocorticoid receptor agonist An agonist that selectively binds to and activates a glucocorticoid receptor.

hormone Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds.

Applications:

anti-inflammatory agent Any compound that has anti-inflammatory effects.

ophthalmology drug Any compound used for the treatment of eye conditions or eye diseases.

prodrug A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.

anti-allergic agent A drug used to treat allergic reactions.

ChEBI Ontology

Outgoing Relation(s)
	prednisolone sodium phosphate (CHEBI:8379) has part prednisolone phosphate(2−) (CHEBI:145706)
	prednisolone sodium phosphate (CHEBI:8379) has role anti-allergic agent (CHEBI:50857)
	prednisolone sodium phosphate (CHEBI:8379) has role anti-inflammatory agent (CHEBI:67079)
	prednisolone sodium phosphate (CHEBI:8379) has role glucocorticoid receptor agonist (CHEBI:63562)
	prednisolone sodium phosphate (CHEBI:8379) has role ophthalmology drug (CHEBI:66981)
	prednisolone sodium phosphate (CHEBI:8379) has role prodrug (CHEBI:50266)
	prednisolone sodium phosphate (CHEBI:8379) is a glucocorticoid (CHEBI:24261)
	prednisolone sodium phosphate (CHEBI:8379) is a organic sodium salt (CHEBI:38700)

IUPAC Name
disodium 11β,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl phosphate

Synonyms	Source
11β,17α-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl phosphate disodium	ChEBI
disodium prednisolone 21-phosphate	ChEBI
prednisolone 21-disodium phosphate	DrugBank
prednisolone 21-phosphate disodium	ChemIDplus
prednisolone disodium phosphate	ChemIDplus
prednisolone sodium phosphate	KEGG DRUG

Brand Names	Source
Codelsol	ChemIDplus
Cortisate-20	ChemIDplus
Hydeltrasol	ChemIDplus
Inflamase	ChemIDplus
Inflamase Forte	ChemIDplus
Metreton	ChemIDplus

Manual Xrefs	Databases
4451	DrugCentral
D00981	KEGG DRUG
DBSALT000785	DrugBank
MX2008015059	Patent
Prednisolone_sodium_phosphate	Wikipedia

Registry Numbers	Sources
Reaxys:4795229	Reaxys
CAS:125-02-0	ChemIDplus

Citations