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CHEBI:83687 - sertaconazole nitrate
| ChEBI ID | CHEBI:83687 |
| ChEBI Name | sertaconazole nitrate |
| Stars | |
| Definition | A racemate comprising equimolar amounts of (R)- and (S)-sertaconazole nitrate. A broad spectrum antifungal with added antipruritic and anti-inflammatory activity used for treatment of various skin infections. |
| Last Modified | 23 July 2015 |
| Submitter | Steve |
| Formula | C20H16Cl3N3O4S |
| Net Charge | 0 |
| Average Mass | 500.783 |
| Monoisotopic Mass | 498.99271 |
| Roles Classification |
|---|
| Biological Roles: | EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of EC 1.14.13.70 (sterol 14α-demethylase). antibacterial drug A drug used to treat or prevent bacterial infections. antifungal drug Any antifungal agent used to prevent or treat fungal infections in humans or animals. antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. antifungal drug Any antifungal agent used to prevent or treat fungal infections in humans or animals. antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. ergosterol biosynthesis inhibitor Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol. antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. ergosterol biosynthesis inhibitor Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol. |
| Applications: | non-steroidal anti-inflammatory drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. antipruritic drug A drug, usually applied topically, that relieves pruritus (itching). antibacterial drug A drug used to treat or prevent bacterial infections. antifungal drug Any antifungal agent used to prevent or treat fungal infections in humans or animals. antifungal drug Any antifungal agent used to prevent or treat fungal infections in humans or animals. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| sertaconazole nitrate (CHEBI:83687) has part (S)-sertaconazole nitrate (CHEBI:83691) |
| sertaconazole nitrate (CHEBI:83687) has part arasertaconazole nitrate (CHEBI:83692) |
| sertaconazole nitrate (CHEBI:83687) has role antibacterial drug (CHEBI:36047) |
| sertaconazole nitrate (CHEBI:83687) has role antipruritic drug (CHEBI:59683) |
| sertaconazole nitrate (CHEBI:83687) has role EC 1.14.13.70 (sterol 14α-demethylase) inhibitor (CHEBI:77884) |
| sertaconazole nitrate (CHEBI:83687) has role non-steroidal anti-inflammatory drug (CHEBI:35475) |
| sertaconazole nitrate (CHEBI:83687) is a conazole antifungal drug (CHEBI:87071) |
| sertaconazole nitrate (CHEBI:83687) is a imidazole antifungal drug (CHEBI:87069) |
| sertaconazole nitrate (CHEBI:83687) is a racemate (CHEBI:60911) |
| IUPAC Name |
|---|
| rac-1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole nitrate |
| Synonyms | Source |
|---|---|
| rac-sertaconazole nitrate | ChEBI |
| (RS)-sertaconazole nitrate | ChEBI |
| racemic sertaconazole nitrate | ChEBI |
| sertaconazole mononitrate | ChEBI |
| (±)-sertaconazole nitrate | ChEBI |
| Brand Names | Source |
|---|---|
| Ertaczo | KEGG DRUG |
| Zalain | KEGG DRUG |
| Manual Xrefs | Databases |
|---|---|
| D08510 | KEGG DRUG |
| DB01153 | DrugBank |
| MX2007002924 | Patent |
| Registry Numbers | Sources |
|---|---|
| Reaxys:5375607 | Reaxys |
| CAS:99592-39-9 | ChemIDplus |
| CAS:99592-39-9 | KEGG DRUG |
| Citations |
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