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CHEBI:83326 - tedizolid phosphate

ChEBI IDCHEBI:83326
ChEBI Nametedizolid phosphate
Stars
DefinitionA phosphate monoester resulting from the formal condensation of equimolar amounts of phosphoric acid with the hydroxy group of tedizolid . It is a prodrug of tedizolid, used for the treatment of acute bacterial skin infections caused by certain susceptible bacteria, including Staphylococcus aureus (including methicillin-resistant strains (MRSA) and methicillin-susceptible strains), various Streptococcus species, and Enterococcus faecalis.
Last Modified22 February 2017
SubmitterSteve
DownloadsMolfile
FormulaC17H16FN6O6P
Net Charge0
Average Mass450.323
Monoisotopic Mass450.08530
SMILESCn1nnc(-c2ccc(-c3ccc(N4C[C@H](COP(=O)(O)O)OC4=O)cc3F)cn2)n1
InChIInChI=1S/C17H16FN6O6P/c1-23-21-16(20-22-23)15-5-2-10(7-19-15)13-4-3-11(6-14(13)18)24-8-12(30-17(24)25)9-29-31(26,27)28/h2-7,12H,8-9H2,1H3,(H2,26,27,28)/t12-/m1/s1
InChIKeyQCGUSIANLFXSGE-GFCCVEGCSA-N
Wikipedia
Roles Classification
Biological Roles:
protein synthesis inhibitor  A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein.
antimicrobial agent  A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
Application:
prodrug  A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
ChEBI Ontology
Outgoing Relation(s)
tedizolid phosphate (CHEBI:83326) has role antimicrobial agent (CHEBI:33281)
tedizolid phosphate (CHEBI:83326) has role prodrug (CHEBI:50266)
tedizolid phosphate (CHEBI:83326) has role protein synthesis inhibitor (CHEBI:48001)
tedizolid phosphate (CHEBI:83326) is a carbamate ester (CHEBI:23003)
tedizolid phosphate (CHEBI:83326) is a organofluorine compound (CHEBI:37143)
tedizolid phosphate (CHEBI:83326) is a oxazolidinone (CHEBI:55374)
tedizolid phosphate (CHEBI:83326) is a phosphate monoester (CHEBI:7794)
tedizolid phosphate (CHEBI:83326) is a pyridines (CHEBI:26421)
tedizolid phosphate (CHEBI:83326) is a tetrazoles (CHEBI:35689)
IUPAC Name 
[(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methyl dihydrogen phosphate
Synonyms  Source
Tedizolid phosphateKEGG DRUG
Torezolid phosphateChemIDplus
TR-701ChEBI
TR-701 FAChemIDplus
Brand Name  Source
SivextroChemIDplus
Manual XrefsDatabases
D09686KEGG DRUG
TedizolidWikipedia
4873DrugCentral
Registry NumbersSources
Reaxys:12031391Reaxys
CAS:856867-55-5KEGG DRUG
CAS:856867-55-5ChemIDplus