EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:82717 - tedizolid

ChEBI IDCHEBI:82717
ChEBI Nametedizolid
Stars
DefinitionA member of the class of pyridines that is pyridine which is substituted by a 2-methyl-2H-tetrazol-5-yl group at position 2 and by a 2-fluoro-4-[(5R)-5-(hydroxymethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl group at position 5. It is used as its phosphate pro-drug used for the treatment of acute bacterial skin and skin structure infections caused by certain susceptible bacteria, including Staphylococcus aureus (including methicillin-resistant strains (MRSA) and methicillin-susceptible strains), various Streptococcus species, and Enterococcus faecalis.
Last Modified15 July 2016
Submittertmorrison
DownloadsMolfile
FormulaC17H15FN6O3
Net Charge0
Average Mass370.344
Monoisotopic Mass370.11897
SMILESCn1nnc(-c2ccc(-c3ccc(N4C[C@H](CO)OC4=O)cc3F)cn2)n1
InChIInChI=1S/C17H15FN6O3/c1-23-21-16(20-22-23)15-5-2-10(7-19-15)13-4-3-11(6-14(13)18)24-8-12(9-25)27-17(24)26/h2-7,12,25H,8-9H2,1H3/t12-/m1/s1
InChIKeyXFALPSLJIHVRKE-GFCCVEGCSA-N
Wikipedia
Roles Classification
Biological Roles:
protein synthesis inhibitor  A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein.
antimicrobial agent  A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
ChEBI Ontology
Outgoing Relation(s)
tedizolid (CHEBI:82717) has role antimicrobial agent (CHEBI:33281)
tedizolid (CHEBI:82717) has role drug metabolite (CHEBI:49103)
tedizolid (CHEBI:82717) has role protein synthesis inhibitor (CHEBI:48001)
tedizolid (CHEBI:82717) is a carbamate ester (CHEBI:23003)
tedizolid (CHEBI:82717) is a organofluorine compound (CHEBI:37143)
tedizolid (CHEBI:82717) is a oxazolidinone (CHEBI:55374)
tedizolid (CHEBI:82717) is a primary alcohol (CHEBI:15734)
tedizolid (CHEBI:82717) is a pyridines (CHEBI:26421)
tedizolid (CHEBI:82717) is a tetrazoles (CHEBI:35689)
IUPAC Name 
(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-5-(hydroxymethyl)-1,3-oxazolidin-2-one
INN  Source
tedizolidKEGG DRUG
Synonyms  Source
TR 700ChemIDplus
TR-700ChemIDplus
DA-7157ChemIDplus
DA 7157ChemIDplus
TorezolidChemIDplus
Manual XrefsDatabases
D09685KEGG DRUG
TedizolidWikipedia
Registry NumbersSources
Reaxys:10589936Reaxys
CAS:856866-72-3KEGG DRUG
CAS:856866-72-3ChemIDplus
Citations