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CHEBI:8107 - phenytoin

Default Structure
ChEBI IDCHEBI:8107
ChEBI Namephenytoin
Stars
DefinitionA imidazolidine-2,4-dione that consists of hydantoin bearing two phenyl substituents at position 5.
Secondary ChEBI IDCHEBI:100921
Last Modified22 February 2017
DownloadsMolfile
FormulaC15H12N2O2
Net Charge0
Average Mass252.273
Monoisotopic Mass252.08988
SMILESO=C1NC(=O)C(c2ccccc2)(c2ccccc2)N1
InChIInChI=1S/C15H12N2O2/c18-13-15(17-14(19)16-13,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H,(H2,16,17,18,19)
InChIKeyCXOFVDLJLONNDW-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Roles:
sodium channel blocker  An agent that inhibits sodium influx through cell membranes.
drug allergen  Any drug which causes the onset of an allergic reaction.
teratogenic agent  A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect.
Applications:
drug allergen  Any drug which causes the onset of an allergic reaction.
anticonvulsant  A drug used to prevent seizures or reduce their severity.
ChEBI Ontology
Outgoing Relation(s)
phenytoin (CHEBI:8107) has functional parent hydantoin (CHEBI:27612)
phenytoin (CHEBI:8107) has role anticonvulsant (CHEBI:35623)
phenytoin (CHEBI:8107) has role drug allergen (CHEBI:88188)
phenytoin (CHEBI:8107) has role sodium channel blocker (CHEBI:38633)
phenytoin (CHEBI:8107) has role teratogenic agent (CHEBI:50905)
phenytoin (CHEBI:8107) is a imidazolidine-2,4-dione (CHEBI:24628)
IUPAC Name 
5,5-diphenylimidazolidine-2,4-dione
INNs  Source
fenitoinaChemIDplus
phenytoinChemIDplus
phenytoineChemIDplus
phenytoinumChemIDplus
Synonyms  Source
5,5-diphenylimidazolidine-2,4-dioneChEMBL
5,5-Diphenyl-imidazolidine-2,4-dioneChEMBL
5,5-diphenyltetrahydro-1H-2,4-imidazoledioneChEMBL
DILANTINChEMBL
PHENTYTOINChEMBL
Manual XrefsDatabases
2152DrugCentral
C07443KEGG COMPOUND
D00512KEGG DRUG
DB00252DrugBank
HMDB0014397HMDB
LSM-5663LINCS
PhenytoinWikipedia
WO2012174723Patent
Registry NumbersSources
Reaxys:384532Reaxys
CAS:57-41-0KEGG COMPOUND
CAS:57-41-0ChemIDplus
Citations