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CHEBI:8107 - phenytoin

Default Structure
ChEBI IDCHEBI:8107
ChEBI Namephenytoin
Stars
DefinitionA imidazolidine-2,4-dione that consists of hydantoin bearing two phenyl substituents at position 5.
Secondary ChEBI IDCHEBI:100921
Last Modified22 February 2017
DownloadsMolfile
FormulaC15H12N2O2
Net Charge0
Average Mass252.273
Monoisotopic Mass252.08988
SMILESO=C1NC(=O)C(c2ccccc2)(c2ccccc2)N1
InChIInChI=1S/C15H12N2O2/c18-13-15(17-14(19)16-13,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H,(H2,16,17,18,19)
InChIKeyCXOFVDLJLONNDW-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Roles:
sodium channel blocker  An agent that inhibits sodium influx through cell membranes.
teratogenic agent  A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect.
drug allergen  Any drug which causes the onset of an allergic reaction.
Applications:
drug allergen  Any drug which causes the onset of an allergic reaction.
anticonvulsant  A drug used to prevent seizures or reduce their severity.
ChEBI Ontology
Outgoing Relation(s)
phenytoin (CHEBI:8107) has functional parent hydantoin (CHEBI:27612)
phenytoin (CHEBI:8107) has role anticonvulsant (CHEBI:35623)
phenytoin (CHEBI:8107) has role drug allergen (CHEBI:88188)
phenytoin (CHEBI:8107) has role sodium channel blocker (CHEBI:38633)
phenytoin (CHEBI:8107) has role teratogenic agent (CHEBI:50905)
phenytoin (CHEBI:8107) is a imidazolidine-2,4-dione (CHEBI:24628)
IUPAC Name 
5,5-diphenylimidazolidine-2,4-dione
INNs  Source
fenitoinaChemIDplus
phenytoinChemIDplus
phenytoineChemIDplus
phenytoinumChemIDplus
Synonyms  Source
5,5-diphenylimidazolidine-2,4-dioneChEMBL
5,5-Diphenyl-imidazolidine-2,4-dioneChEMBL
5,5-diphenyltetrahydro-1H-2,4-imidazoledioneChEMBL
DILANTINChEMBL
PHENTYTOINChEMBL
Manual XrefsDatabases
2152DrugCentral
C07443KEGG COMPOUND
D00512KEGG DRUG
DB00252DrugBank
HMDB0014397HMDB
LSM-5663LINCS
PhenytoinWikipedia
WO2012174723Patent
Registry NumbersSources
Reaxys:384532Reaxys
CAS:57-41-0KEGG COMPOUND
CAS:57-41-0ChemIDplus
Citations