CHEBI:8064 - phenformin

ChEBI IDCHEBI:8064
ChEBI Namephenformin
Stars
DefinitionA member of the class of biguanides that is biguanide in which one of the terminal nitrogen atoms is substituted by a 2-phenylethyl group. It was used as an anti-diabetic drug but was later withdrawn from the market due to potential risk of lactic acidosis.
Last Modified28 October 2021
DownloadsMolfile
FormulaC10H15N5
Net Charge0
Average Mass205.265
Monoisotopic Mass205.13275
SMILESN=C(N)NC(=N)NCCc1ccccc1
InChIInChI=1S/C10H15N5/c11-9(12)15-10(13)14-7-6-8-4-2-1-3-5-8/h1-5H,6-7H2,(H6,11,12,13,14,15)
InChIKeyICFJFFQQTFMIBG-UHFFFAOYSA-N
Wikipedia
Roles Classification
Applications:
geroprotector  Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
hypoglycemic agent  A drug which lowers the blood glucose level.
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
hypoglycemic agent  A drug which lowers the blood glucose level.
ChEBI Ontology
Outgoing Relation(s)
phenformin (CHEBI:8064) has functional parent biguanide (CHEBI:3095)
phenformin (CHEBI:8064) has role antineoplastic agent (CHEBI:35610)
phenformin (CHEBI:8064) has role geroprotector (CHEBI:176497)
phenformin (CHEBI:8064) has role hypoglycemic agent (CHEBI:35526)
phenformin (CHEBI:8064) is a biguanides (CHEBI:53662)
IUPAC Name 
N-(2-phenylethyl)imidodicarbonimidic diamide
INNs  Source
fenforminaChemIDplus
phenforminumChemIDplus
phenforminChemIDplus
phenformineChemIDplus
Synonym  Source
DBIKEGG COMPOUND
Manual XrefsDatabases
C07673KEGG COMPOUND
D08351KEGG DRUG
HMDB0015050HMDB
DB00914DrugBank
PhenforminWikipedia
WO2010114805Patent
US2961377Patent
US3057780Patent
LSM-2233LINCS
2126DrugCentral
8CVPDBeChem
Registry NumbersSources
Reaxys:1977317Reaxys
CAS:114-86-3KEGG COMPOUND
CAS:114-86-3ChemIDplus
CAS:114-86-3NIST Chemistry WebBook
Citations