CHEBI:8058 - phencyclidine

ChEBI IDCHEBI:8058
ChEBI Namephencyclidine
Stars
DefinitionA member of the class of piperidines that is piperidine in which the nitrogen is substituted with a 1-phenylcyclohexyl group. Formerly used as an anaesthetic agent, it exhibits both hallucinogenic and neurotoxic effects.
Last Modified22 February 2017
DownloadsMolfile
FormulaC17H25N
Net Charge0
Average Mass243.394
Monoisotopic Mass243.19870
SMILESc1ccc(C2(N3CCCCC3)CCCCC2)cc1
InChIInChI=1S/C17H25N/c1-4-10-16(11-5-1)17(12-6-2-7-13-17)18-14-8-3-9-15-18/h1,4-5,10-11H,2-3,6-9,12-15H2
InChIKeyJTJMJGYZQZDUJJ-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Roles:
NMDA receptor antagonist  Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs.
neurotoxin  A poison that interferes with the functions of the nervous system.
Applications:
anaesthetic  Substance which produces loss of feeling or sensation.
psychotropic drug  A loosely defined grouping of drugs that have effects on psychological function.
ChEBI Ontology
Outgoing Relation(s)
phencyclidine (CHEBI:8058) has parent hydride piperidine (CHEBI:18049)
phencyclidine (CHEBI:8058) has role anaesthetic (CHEBI:38867)
phencyclidine (CHEBI:8058) has role neurotoxin (CHEBI:50910)
phencyclidine (CHEBI:8058) has role NMDA receptor antagonist (CHEBI:60643)
phencyclidine (CHEBI:8058) has role psychotropic drug (CHEBI:35471)
phencyclidine (CHEBI:8058) is a benzenes (CHEBI:22712)
phencyclidine (CHEBI:8058) is a piperidines (CHEBI:26151)
IUPAC Name 
1-(1-phenylcyclohexyl)piperidine
INNs  Source
phencyclidinumChemIDplus
fenciclidinaChemIDplus
phencyclidineChemIDplus
Synonyms  Source
PhencyclidineKEGG COMPOUND
PCPChemIDplus
Manual XrefsDatabases
C07575KEGG COMPOUND
PhencyclidineWikipedia
DB03575DrugBank
1PCPDBeChem
2121DrugCentral
Registry NumbersSources
Reaxys:20976544Reaxys
CAS:77-10-1KEGG COMPOUND
CAS:77-10-1ChemIDplus
Citations