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CHEBI:7953 - pemoline

ChEBI IDCHEBI:7953
ChEBI Namepemoline
Stars
DefinitionA member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted by an amino group at position 2 and by a phenyl group at position 5. A central nervous system stimulant, it was used to treat hyperactivity disorders in children, but withdrawn from use following reports of serious hepatotoxicity.
Last Modified22 February 2017
DownloadsMolfile
FormulaC9H8N2O2
Net Charge0
Average Mass176.175
Monoisotopic Mass176.05858
SMILESNC1=NC(=O)C(c2ccccc2)O1
InChIInChI=1S/C9H8N2O2/c10-9-11-8(12)7(13-9)6-4-2-1-3-5-6/h1-5,7H,(H2,10,11,12)
InChIKeyNRNCYVBFPDDJNE-UHFFFAOYSA-N
Wikipedia
Roles Classification
Application:
central nervous system stimulant  Any drug that enhances the activity of the central nervous system.
ChEBI Ontology
Outgoing Relation(s)
pemoline (CHEBI:7953) has role central nervous system stimulant (CHEBI:35337)
pemoline (CHEBI:7953) is a 1,3-oxazoles (CHEBI:46812)
IUPAC Name 
2-amino-5-phenyl-1,3-oxazol-4(5H)-one
INNs  Source
pémolineWHO MedNet
pemolinumWHO MedNet
pemolineWHO MedNet
pemolinaWHO MedNet
Synonyms  Source
5-phenyl-2-imino-4-oxazolidinoneChemIDplus
5-phenyl-2-imino-4-oxooxazolidineChemIDplus
5-phenylisohydantionChemIDplus
2-Amino-5-phenyl-4(5H)-oxazoloneChemIDplus
2-imino-4-keto-5-phenyltetrahydrooxazoleChemIDplus
2-imino-5-phenyl-4-oxazolidinoneChemIDplus
Brand Names  Source
CylertKEGG DRUG
MyaminDrugBank
NotairDrugBank
HytonDrugBank
BetanaminDrugBank
NitanDrugBank
Manual XrefsDatabases
C07899KEGG COMPOUND
D00744KEGG DRUG
DB01230DrugBank
PemolineWikipedia
LSM-5159LINCS
2075DrugCentral
Registry NumbersSources
Reaxys:151559Reaxys
CAS:2152-34-3KEGG COMPOUND
CAS:2152-34-3ChemIDplus
CAS:2152-34-3NIST Chemistry WebBook
Citations