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CHEBI:78777 - polyoxorim

ChEBI IDCHEBI:78777
ChEBI Namepolyoxorim
Stars
DefinitionA member of the class of polyoxins that is isolated from the soil organism Streptomyces cacaoi var. asoensis. Polyoxorim exhibits fungicidal properties and may be used on rice, industrial grounds, golf courses and parks.
Last Modified23 July 2015
SubmitterSteve
DownloadsMolfile
FormulaC17H23N5O14
Net Charge0
Average Mass521.392
Monoisotopic Mass521.12415
SMILES[H][C@]1([C@H](NC(=O)[C@@H](N)[C@H](O)[C@@H](O)COC(N)=O)C(=O)O)O[C@@H](n2cc(C(=O)O)c(=O)nc2=O)[C@H](O)[C@@H]1O
InChIInChI=1S/C17H23N5O14/c18-5(7(24)4(23)2-35-16(19)33)12(28)20-6(15(31)32)10-8(25)9(26)13(36-10)22-1-3(14(29)30)11(27)21-17(22)34/h1,4-10,13,23-26H,2,18H2,(H2,19,33)(H,20,28)(H,29,30)(H,31,32)(H,21,27,34)/t4-,5-,6-,7+,8-,9+,10+,13+/m0/s1
InChIKeyJPFWJDMDPLEUBD-ITJAGOAWSA-N
Species of MetaboliteComponentSourceComments
Streptomyces cacaoi var. asoensis (ncbitaxon:249586) - PubMed (Citation: Isono, K., Nagatsu, J., Kawashima, Y., and Suzuki, S. "Studies on polyoxins, antifungal antibiotics. Part I. Isolation and characterization of polyoxins A and B." Agric. Biol. Chem. (1965) 29:848-854. (No PubMed record available.))
Roles Classification
Biological Roles:
EC 2.4.1.16 (chitin synthase) inhibitor  A EC 2.4.1.* (hexosyltransferase) inhibitor that inhibits the action of chitin synthase (EC 2.4.1.16).
antifungal agrochemical  Any substance used in acriculture, horticulture, forestry, etc. for its fungicidal properties.
EC 2.4.1.16 (chitin synthase) inhibitor  A EC 2.4.1.* (hexosyltransferase) inhibitor that inhibits the action of chitin synthase (EC 2.4.1.16).
bacterial metabolite  Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
fungicide  A substance used to destroy fungal pests.
antifungal agent  An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
antifungal agent  An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
Applications:
antifungal agrochemical  Any substance used in acriculture, horticulture, forestry, etc. for its fungicidal properties.
fungicide  A substance used to destroy fungal pests.
ChEBI Ontology
Outgoing Relation(s)
polyoxorim (CHEBI:78777) has role antifungal agrochemical (CHEBI:86328)
polyoxorim (CHEBI:78777) has role EC 2.4.1.16 (chitin synthase) inhibitor (CHEBI:59672)
polyoxorim (CHEBI:78777) is a antibiotic fungicide (CHEBI:87114)
polyoxorim (CHEBI:78777) is a polyoxin (CHEBI:26194)
IUPAC Name 
1-{(2R,3R,4S,5R)-5-[(S)-{[(2S,3S,4S)-2-amino-5-(carbamoyloxy)-3,4-dihydroxypentanoyl]amino}(carboxy)methyl]-3,4-dihydroxytetrahydrofuran-2-yl}-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid
Synonyms  Source
Polyoxin ZChemIDplus
Polyoxin DChemIDplus
Manual XrefsDatabases
polyoxorimAlan Wood's Pesticides
2064BPDB
Registry NumbersSources
Reaxys:969003Reaxys
CAS:22976-86-9ChemIDplus
Citations