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CHEBI:78677 - 6-anilino-5,8-quinolinedione

ChEBI IDCHEBI:78677
ChEBI Name6-anilino-5,8-quinolinedione
Stars
DefinitionA quinolone that is quinoline-5,8-dione in which the hydrogen at position 6 is replaced by an anilino group.
Last Modified8 July 2025
SubmitterSteve
DownloadsMolfile
FormulaC15H10N2O2
Net Charge0
Average Mass250.257
Monoisotopic Mass250.07423
SMILESO=C1C(Nc2ccccc2)=CC(=O)c2ncccc21
InChIInChI=1S/C15H10N2O2/c18-13-9-12(17-10-5-2-1-3-6-10)15(19)11-7-4-8-16-14(11)13/h1-9,17H
InChIKeyGXIJYWUWLNHKNW-UHFFFAOYSA-N
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Role:
EC 4.6.1.2 (guanylate cyclase) inhibitor  An EC 4.6.* (P‒O lyase) inhibitor that interferes with the action of enzyme guanylate cyclase (EC 4.6.1.2).
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
6-anilino-5,8-quinolinedione (CHEBI:78677) has role antineoplastic agent (CHEBI:35610)
6-anilino-5,8-quinolinedione (CHEBI:78677) has role EC 4.6.1.2 (guanylate cyclase) inhibitor (CHEBI:78678)
6-anilino-5,8-quinolinedione (CHEBI:78677) is a p-quinones (CHEBI:25830)
6-anilino-5,8-quinolinedione (CHEBI:78677) is a aminoquinoline (CHEBI:36709)
6-anilino-5,8-quinolinedione (CHEBI:78677) is a aromatic amine (CHEBI:33860)
6-anilino-5,8-quinolinedione (CHEBI:78677) is a quinolone (CHEBI:23765)
IUPAC Name 
6-anilinoquinoline-5,8-dione
Synonyms  Source
6-(Phenylamino)-5,8-quinolinedioneChemIDplus
LY 83583ChemIDplus
LY-83583ChemIDplus
LY83583ChEBI
Manual XrefsDatabases
LSM-3393LINCS
HMDB0247642HMDB
Registry NumbersSources
Reaxys:207004Reaxys
CAS:91300-60-6ChemIDplus
Citations