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CHEBI:7863 - oxymetazoline hydrochloride

ChEBI IDCHEBI:7863
ChEBI Nameoxymetazoline hydrochloride
Stars
DefinitionA hydrochloride salt resulting from the reaction of equimolar quantities of oxymetazoline and hydrogen chloride. A direct-acting sympathomimetic with marked α-adrenergic activity, it is a vasoconstrictor that is used to relieve nasal congestion.
Last Modified17 March 2014
DownloadsMolfile
FormulaC16H24N2O.HCl
Net Charge0
Average Mass296.842
Monoisotopic Mass296.16554
SMILESCc1cc(C(C)(C)C)c(O)c(C)c1CC1=NCCN1.Cl
InChIInChI=1S/C16H24N2O.ClH/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14;/h8,19H,6-7,9H2,1-5H3,(H,17,18);1H
InChIKeyBEEDODBODQVSIM-UHFFFAOYSA-N
Roles Classification
Biological Roles:
sympathomimetic agent  A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
alpha-adrenergic agonist  An agent that selectively binds to and activates α-adrenergic receptors.
Applications:
sympathomimetic agent  A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
vasoconstrictor agent  Drug used to cause constriction of the blood vessels.
nasal decongestant  A drug used to relieve nasal congestion in the upper respiratory tract.
alpha-adrenergic agonist  An agent that selectively binds to and activates α-adrenergic receptors.
ChEBI Ontology
Outgoing Relation(s)
oxymetazoline hydrochloride (CHEBI:7863) has part oxymetazoline(1+) (CHEBI:77716)
oxymetazoline hydrochloride (CHEBI:7863) has role nasal decongestant (CHEBI:77715)
oxymetazoline hydrochloride (CHEBI:7863) has role sympathomimetic agent (CHEBI:35524)
oxymetazoline hydrochloride (CHEBI:7863) has role vasoconstrictor agent (CHEBI:50514)
oxymetazoline hydrochloride (CHEBI:7863) has role α-adrenergic agonist (CHEBI:35569)
oxymetazoline hydrochloride (CHEBI:7863) is a hydrochloride (CHEBI:36807)
IUPAC Names 
2-(4-tert-butyl-3-hydroxy-2,6-dimethylbenzyl)-4,5-dihydro-1H-imidazol-1-ium chloride
6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol hydrochloride
Synonyms  Source
2,6-dimethyl-2-(4-tertiarybutyl-3-hydroxyphenyl)methylimidazoline hydrochlorideChemIDplus
2-(4-t-butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazolinium chlorideChemIDplus
oxymetazoline HClChemIDplus
Brand Names  Source
OcuclearKEGG DRUG
SinexChemIDplus
AfrazineChemIDplus
Manual XrefsDatabases
D01022KEGG DRUG
DB00935DrugBank
HMDB0015070HMDB
Registry NumbersSources
Reaxys:5462995Reaxys
CAS:2315-02-8ChemIDplus
Citations