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CHEBI:77954 - 2-(2-amino-3-methoxyphenyl)chromen-4-one

ChEBI IDCHEBI:77954
ChEBI Name2-(2-amino-3-methoxyphenyl)chromen-4-one
Stars
DefinitionA member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
Last Modified27 October 2021
SubmitterSteve
DownloadsMolfile
FormulaC16H13NO3
Net Charge0
Average Mass267.284
Monoisotopic Mass267.08954
SMILESCOc1cccc(-c2cc(=O)c3ccccc3o2)c1N
InChIInChI=1S/C16H13NO3/c1-19-14-8-4-6-11(16(14)17)15-9-12(18)10-5-2-3-7-13(10)20-15/h2-9H,17H2,1H3
InChIKeyQFWCYNPOPKQOKV-UHFFFAOYSA-N
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Role:
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor  An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of mitogen-activated protein kinase (EC 2.7.11.24).
Application:
geroprotector  Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
ChEBI Ontology
Outgoing Relation(s)
2-(2-amino-3-methoxyphenyl)chromen-4-one (CHEBI:77954) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
2-(2-amino-3-methoxyphenyl)chromen-4-one (CHEBI:77954) has role geroprotector (CHEBI:176497)
2-(2-amino-3-methoxyphenyl)chromen-4-one (CHEBI:77954) is a aromatic amine (CHEBI:33860)
2-(2-amino-3-methoxyphenyl)chromen-4-one (CHEBI:77954) is a monomethoxyflavone (CHEBI:25401)
IUPAC Name 
2-(2-amino-3-methoxyphenyl)-4H-chromen-4-one
Synonyms  Source
PD 98,059ChemIDplus
PD 98059ChemIDplus
2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-oneChemIDplus
2'-amino-3'-methoxyflavoneChEBI
PD-98059ChemIDplus
PD98059ChemIDplus
Manual XrefsDatabases
LSM-3394LINCS
HMDB0244751HMDB
4551ChemSpider
Registry NumbersSources
Reaxys:8148190Reaxys
CAS:167869-21-8ChemIDplus
Citations