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CHEBI:77942 - tavaborole

Default Structure
ChEBI IDCHEBI:77942
ChEBI Nametavaborole
Stars
DefinitionA member of the class of benzoxaboroles that is 1,3-dihydro-1-hydroxy-2,1-benzoxaborole substituted at position 5 by a fluoro group. A topical antifungal agent used for the treatment of onychomycosis (fungal infection of the toenails and fingernails).
Last Modified22 February 2017
SubmitterSteve
DownloadsMolfile
FormulaC7H6BFO2
Net Charge0
Average Mass151.933
Monoisotopic Mass152.04449
SMILESOB1OCc2cc(F)ccc21
InChIInChI=1S/C7H6BFO2/c9-6-1-2-7-5(3-6)4-11-8(7)10/h1-3,10H,4H2
InChIKeyLFQDNHWZDQTITF-UHFFFAOYSA-N
Roles Classification
Biological Roles:
EC 6.1.1.4 (leucine--tRNA ligase) inhibitor  An EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor that inhibits the action of leucine—tRNA synthetase (EC 6.1.1.4).
protein synthesis inhibitor  A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein.
antifungal agent  An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
ChEBI Ontology
Outgoing Relation(s)
tavaborole (CHEBI:77942) has role antifungal agent (CHEBI:35718)
tavaborole (CHEBI:77942) has role EC 6.1.1.4 (leucine—tRNA ligase) inhibitor (CHEBI:77953)
tavaborole (CHEBI:77942) has role protein synthesis inhibitor (CHEBI:48001)
tavaborole (CHEBI:77942) is a benzoxaborole (CHEBI:78240)
tavaborole (CHEBI:77942) is a organofluorine compound (CHEBI:37143)
IUPAC Name 
5-fluoro-2,1-benzoxaborol-1(3H)-ol
Synonyms  Source
5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaboroleChemIDplus
AN 2690ChemIDplus
AN-2690ChemIDplus
AN2690ChemIDplus
Manual XrefsDatabases
4877DrugCentral
D10169KEGG DRUG
Registry NumbersSources
Reaxys:10657796Reaxys
CAS:174671-46-6KEGG DRUG
CAS:174671-46-6ChemIDplus
Citations