EMBL-EBI | Chemical Biology | ChEBI
Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search
We are looking for a new Chemistry curator to join the ChEBI team. Find out more about it here.
CHEBI:7773 - Ondansetron
| Formula | C18H19N3O |
| Net Charge | 0 |
| Average Mass | 293.370 |
| Monoisotopic Mass | 293.15281 |
| SMILES | Cc1nccn1CC1CCc2c(c3ccccc3n2C)C1=O |
| InChI | InChI=1S/C18H19N3O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2/h3-6,9-10,13H,7-8,11H2,1-2H3 |
| InChIKey | FELGMEQIXOGIFQ-UHFFFAOYSA-N |
| Roles Classification |
|---|
| Biological Roles: | anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. |
| Applications: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. gastrointestinal drug A drug used for its effects on the gastrointestinal system, e.g. controlling gastric acidity, regulating gastrointestinal motility and water flow, and improving digestion. neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. antispasmodic drug A drug that suppresses spasms. These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder. antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. antiemetic A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors. antidiarrhoeal drug Any drug found useful in the symptomatic treatment of diarrhoea. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| Ondansetron (CHEBI:7773) has role analgesic (CHEBI:35480) |
| Ondansetron (CHEBI:7773) has role anti-HIV agent (CHEBI:64946) |
| Ondansetron (CHEBI:7773) has role antidiarrhoeal drug (CHEBI:55323) |
| Ondansetron (CHEBI:7773) has role antiemetic (CHEBI:50919) |
| Ondansetron (CHEBI:7773) has role antineoplastic agent (CHEBI:35610) |
| Ondansetron (CHEBI:7773) has role antipsychotic agent (CHEBI:35476) |
| Ondansetron (CHEBI:7773) has role antispasmodic drug (CHEBI:53784) |
| Ondansetron (CHEBI:7773) has role gastrointestinal drug (CHEBI:55324) |
| Ondansetron (CHEBI:7773) has role neuroprotective agent (CHEBI:63726) |
| Ondansetron (CHEBI:7773) is a carbazoles (CHEBI:48513) |
| Synonyms | Source |
|---|---|
| A04AA01 | ChEMBL |
| Desmethylondansetron | ChEMBL |
| EUR-1025 | ChEMBL |
| GR-38032 | ChEMBL |
| GR-38032F | DrugCentral |
| GR38032F | DrugCentral |
| Brand Names | Source |
|---|---|
| Zofran odt | ChEMBL |
| Zuplenz | ChEMBL |
| Manual Xrefs | Databases |
|---|---|
| 1992 | DrugCentral |
| C07325 | KEGG COMPOUND |
| D00456 | KEGG DRUG |
| HMDB0005035 | HMDB |
| LSM-1375 | LINCS |
| Registry Numbers | Sources |
|---|---|
| CAS:99614-02-5 | KEGG COMPOUND |
| Citations |
|---|