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CHEBI:77572 - tranilast

ChEBI IDCHEBI:77572
ChEBI Nametranilast
Stars
DefinitionAn amidobenzoic acid that is anthranilic acid in which one of the anilino hydrogens is replaced by a 3,4-dimethoxycinnamoyl group.
Last Modified7 March 2018
SubmitterSteve
DownloadsMolfile
FormulaC18H17NO5
Net Charge0
Average Mass327.336
Monoisotopic Mass327.11067
SMILESCOc1ccc(/C=C/C(=O)Nc2ccccc2C(=O)O)cc1OC
InChIInChI=1S/C18H17NO5/c1-23-15-9-7-12(11-16(15)24-2)8-10-17(20)19-14-6-4-3-5-13(14)18(21)22/h3-11H,1-2H3,(H,19,20)(H,21,22)/b10-8+
InChIKeyNZHGWWWHIYHZNX-CSKARUKUSA-N
Wikipedia
Roles Classification
Chemical Role:
Bronsted acid  A molecular entity capable of donating a hydron to an acceptor (Brønsted base).
Biological Roles:
aryl hydrocarbon receptor agonist  An agonist that binds to and activates aryl hydrocarbon receptors (AhRs).
calcium channel blocker  One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools.
Applications:
hepatoprotective agent  Any compound that is able to prevent damage to the liver.
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
anti-asthmatic drug  A drug used to treat asthma.
nephroprotective agent  Any protective agent that is able to prevent damage to the kidney.
anti-allergic agent  A drug used to treat allergic reactions.
ChEBI Ontology
Outgoing Relation(s)
tranilast (CHEBI:77572) has functional parent anthranilic acid (CHEBI:30754)
tranilast (CHEBI:77572) has role anti-allergic agent (CHEBI:50857)
tranilast (CHEBI:77572) has role anti-asthmatic drug (CHEBI:49167)
tranilast (CHEBI:77572) has role antineoplastic agent (CHEBI:35610)
tranilast (CHEBI:77572) has role aryl hydrocarbon receptor agonist (CHEBI:72768)
tranilast (CHEBI:77572) has role calcium channel blocker (CHEBI:38215)
tranilast (CHEBI:77572) has role hepatoprotective agent (CHEBI:62868)
tranilast (CHEBI:77572) has role nephroprotective agent (CHEBI:76595)
tranilast (CHEBI:77572) is a amidobenzoic acid (CHEBI:48470)
tranilast (CHEBI:77572) is a cinnamamides (CHEBI:23247)
tranilast (CHEBI:77572) is a dimethoxybenzene (CHEBI:51681)
tranilast (CHEBI:77572) is a secondary carboxamide (CHEBI:140325)
IUPAC Name 
2-{[(2E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]amino}benzoic acid
INNs  Source
tranilastKEGG DRUG
tranilastumChemIDplus
tranilastWHO MedNet
tranilastWHO MedNet
Synonyms  Source
N-(3,4-Dimethoxycinnamoyl)anthranilic acidChemIDplus
MK 341ChemIDplus
MK-341ChemIDplus
Brand Name  Source
RizabenKEGG DRUG
Manual XrefsDatabases
D02027KEGG DRUG
TranilastWikipedia
D27PDBeChem
2714DrugCentral
Registry NumbersSources
Reaxys:3085768Reaxys
CAS:53902-12-8KEGG DRUG
CAS:53902-12-8ChemIDplus
Citations