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CHEBI:76749 - bopindolol
| ChEBI ID | CHEBI:76749 |
| ChEBI Name | bopindolol |
| Stars | |
| Definition | A racemate comprising of equal amounts of (R)-bopindolol and (S)-bopindolol. It is a non-selective antagonist of β1- and β2-adrenoceptors and a prodrug in which the ester group is hydrolysed to form the corresponding hydroxy derivative. |
| Last Modified | 14 July 2021 |
| Submitter | Gareth Owen |
| Wikipedia |
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| Roles Classification |
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| Biological Role: | beta-adrenergic antagonist An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety. |
| Applications: | beta-adrenergic antagonist An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety. antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| bopindolol (CHEBI:76749) has part (R)-bopindolol (CHEBI:143780) |
| bopindolol (CHEBI:76749) has part (S)-bopindolol (CHEBI:143781) |
| bopindolol (CHEBI:76749) has role antihypertensive agent (CHEBI:35674) |
| bopindolol (CHEBI:76749) has role β-adrenergic antagonist (CHEBI:35530) |
| bopindolol (CHEBI:76749) is a racemate (CHEBI:60911) |
| IUPAC Name |
|---|
| rac-1-(tert-butylamino)-3-[(2-methyl-1H-indol-4-yl)oxy]propan-2-yl benzoate |
| INNs | Source |
|---|---|
| bopindololum | WHO MedNet |
| bopindolol | WHO MedNet |
| bopindolol | WHO MedNet |
| bopindolol | WHO MedNet |
| Synonyms | Source |
|---|---|
| LT 31-200 | ChemIDplus |
| (±)-bopindolol | ChemIDplus |
| (RS)-bopindolol | ChEBI |
| rac-bopindolol | ChEBI |
| racemic bopindolol | ChEBI |
| (±)-1-[(1,1-Dimethylethyl)amino]-3-[(2-methyl-1H-indol-4-yl)oxy]-2-propanol benzoate | ChEBI |
| Brand Name | Source |
|---|---|
| Sandonorm | KEGG DRUG |
| Manual Xrefs | Databases |
|---|---|
| D07537 | KEGG DRUG |
| 389 | DrugCentral |
| DB08807 | DrugBank |
| HMDB0015696 | HMDB |
| Bopindolol | Wikipedia |
| LSM-45796 | LINCS |
| 40146 | ChemSpider |
| Registry Numbers | Sources |
|---|---|
| CAS:62658-63-3 | ChemIDplus |
| CAS:62658-63-3 | DrugBank |
| Citations |
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