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CHEBI:76749 - bopindolol
| ChEBI ID | CHEBI:76749 |
| ChEBI Name | bopindolol |
| Stars | |
| Definition | A racemate comprising of equal amounts of (R)-bopindolol and (S)-bopindolol. It is a non-selective antagonist of β1- and β2-adrenoceptors and a prodrug in which the ester group is hydrolysed to form the corresponding hydroxy derivative. |
| Last Modified | 14 July 2021 |
| Submitter | Gareth Owen |
| Wikipedia |
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| Roles Classification |
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| Biological Role: | beta-adrenergic antagonist An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety. |
| Applications: | antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. beta-adrenergic antagonist An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| bopindolol (CHEBI:76749) has part (R)-bopindolol (CHEBI:143780) |
| bopindolol (CHEBI:76749) has part (S)-bopindolol (CHEBI:143781) |
| bopindolol (CHEBI:76749) has role antihypertensive agent (CHEBI:35674) |
| bopindolol (CHEBI:76749) has role β-adrenergic antagonist (CHEBI:35530) |
| bopindolol (CHEBI:76749) is a racemate (CHEBI:60911) |
| IUPAC Name |
|---|
| rac-1-(tert-butylamino)-3-[(2-methyl-1H-indol-4-yl)oxy]propan-2-yl benzoate |
| INNs | Source |
|---|---|
| bopindolol | WHO MedNet |
| bopindolol | WHO MedNet |
| bopindolol | WHO MedNet |
| bopindololum | WHO MedNet |
| Synonyms | Source |
|---|---|
| (±)-1-[(1,1-Dimethylethyl)amino]-3-[(2-methyl-1H-indol-4-yl)oxy]-2-propanol benzoate | ChEBI |
| (±)-bopindolol | ChemIDplus |
| rac-bopindolol | ChEBI |
| (RS)-bopindolol | ChEBI |
| LT 31-200 | ChemIDplus |
| racemic bopindolol | ChEBI |
| Brand Name | Source |
|---|---|
| Sandonorm | KEGG DRUG |
| Manual Xrefs | Databases |
|---|---|
| 389 | DrugCentral |
| 40146 | ChemSpider |
| Bopindolol | Wikipedia |
| D07537 | KEGG DRUG |
| DB08807 | DrugBank |
| HMDB0015696 | HMDB |
| LSM-45796 | LINCS |
| Registry Numbers | Sources |
|---|---|
| CAS:62658-63-3 | DrugBank |
| CAS:62658-63-3 | ChemIDplus |
| Citations |
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