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CHEBI:7627 - norethisterone
| Formula | C20H26O2 |
| Net Charge | 0 |
| Average Mass | 298.426 |
| Monoisotopic Mass | 298.19328 |
| SMILES | [H][C@@]12CCC3=CC(=O)CC[C@]3([H])[C@@]1([H])CC[C@@]1(C)[C@@]2([H])CC[C@@]1(O)C#C |
| InChI | InChI=1S/C20H26O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,12,15-18,22H,4-11H2,2H3/t15-,16+,17+,18-,19-,20-/m0/s1 |
| InChIKey | VIKNJXKGJWUCNN-XGXHKTLJSA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | progestin A synthetic progestogen. antiviral agent A substance that destroys or inhibits replication of viruses. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. |
| Applications: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. synthetic oral contraceptive An oral contraceptive which owes its effectiveness to synthetic preparation. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| norethisterone (CHEBI:7627) has parent hydride estrane (CHEBI:23966) |
| norethisterone (CHEBI:7627) has role analgesic (CHEBI:35480) |
| norethisterone (CHEBI:7627) has role antineoplastic agent (CHEBI:35610) |
| norethisterone (CHEBI:7627) has role antiviral agent (CHEBI:22587) |
| norethisterone (CHEBI:7627) has role immunosuppressive agent (CHEBI:35705) |
| norethisterone (CHEBI:7627) has role progestin (CHEBI:59826) |
| norethisterone (CHEBI:7627) has role synthetic oral contraceptive (CHEBI:49326) |
| norethisterone (CHEBI:7627) is a 17β-hydroxy steroid (CHEBI:35343) |
| norethisterone (CHEBI:7627) is a 3-oxo-Δ4 steroid (CHEBI:47909) |
| norethisterone (CHEBI:7627) is a terminal acetylenic compound (CHEBI:73477) |
| norethisterone (CHEBI:7627) is a tertiary alcohol (CHEBI:26878) |
| Incoming Relation(s) |
| norethisterone acetate (CHEBI:7628) has functional parent norethisterone (CHEBI:7627) |
| IUPAC Names |
|---|
| 17-ethynyl-17β-hydroxyestr-4-en-3-one |
| (17α)-17-hydroxy-19-norpregn-4-en-20-yn-3-one |
| INNs | Source |
|---|---|
| norethisterone | KEGG DRUG |
| noréthistérone | WHO MedNet |
| norethisteronum | ChemIDplus |
| noretisterona | ChemIDplus |
| Synonyms | Source |
|---|---|
| (17alpha)-17-ethynyl-17-hydroxyestra-4,8(14),9-trien-3-one | PDBeChem |
| 17-hydroxy-19-nor-17-α-pregn-4-en-20-yn-3-one | ChemIDplus |
| 17-hydroxy-19-nor-17α-pregn-4-en-20-yn-3-one | ChemIDplus |
| 17α-ethinyl-19-nortestosterone | NIST Chemistry WebBook |
| 17α-ethinylestra-4-en-17β-ol-3-one | NIST Chemistry WebBook |
| 17-α-ethynyl-17-hydroxy-4-estren-3-one | ChemIDplus |
| Brand Names | Source |
|---|---|
| Camila | KEGG DRUG |
| Conludag | ChemIDplus |
| Errin | ChEMBL |
| Heather | ChEMBL |
| Incassia | ChEMBL |
| Jencycla | ChEMBL |
| Manual Xrefs | Databases |
|---|---|
| 1962 | DrugCentral |
| C05028 | KEGG COMPOUND |
| D00182 | KEGG DRUG |
| DB00717 | DrugBank |
| HMDB0014855 | HMDB |
| LMST02030097 | LIPID MAPS |
| NDR | PDBeChem |
| Norethisterone | Wikipedia |
| US2744122 | Patent |
| US2849462 | Patent |
| Citations |
|---|