CHEBI:76252 - mofebutazone

ChEBI IDCHEBI:76252
ChEBI Namemofebutazone
Stars
DefinitionA pyrazolidine that is phenylbutazone lacking one of the phenyl substituents. It is used for treatment of joint and muscular pain.
Last Modified22 February 2017
SubmitterSteve
DownloadsMolfile
FormulaC13H16N2O2
Net Charge0
Average Mass232.283
Monoisotopic Mass232.12118
SMILESCCCCC1C(=O)NN(c2ccccc2)C1=O
InChIInChI=1S/C13H16N2O2/c1-2-3-9-11-12(16)14-15(13(11)17)10-7-5-4-6-8-10/h4-8,11H,2-3,9H2,1H3,(H,14,16)
InChIKeyREOJLIXKJWXUGB-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Role:
non-narcotic analgesic  A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
Applications:
non-narcotic analgesic  A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
non-steroidal anti-inflammatory drug  An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
ChEBI Ontology
Outgoing Relation(s)
mofebutazone (CHEBI:76252) has role non-narcotic analgesic (CHEBI:35481)
mofebutazone (CHEBI:76252) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
mofebutazone (CHEBI:76252) is a pyrazolidines (CHEBI:38312)
IUPAC Name 
4-butyl-1-phenylpyrazolidine-3,5-dione
INNs  Source
mofebutazoneKEGG DRUG
mofebutazonumChemIDplus
mofebutazonaChemIDplus
mofébutazoneWHO MedNet
nabumétoneWHO MedNet
Synonyms  Source
2-Phenyl-3,5-dihydroxy-4-butylpyrazolidineChemIDplus
2 FdbpChemIDplus
4-Butyl-1-phenyl-3,5-pyrazolidinedioneChemIDplus
4-Butyl-1-phenyl-3,5-dioxopyrazolidineChemIDplus
MonophenylbutazoneChemIDplus
MophebutazoneChemIDplus
Brand Name  Source
MonazoneKEGG DRUG
Manual XrefsDatabases
MofebutazoneWikipedia
1828DrugCentral
Registry NumbersSources
Reaxys:213056Reaxys
CAS:2210-63-1ChemIDplus
CAS:2210-63-1NIST Chemistry WebBook
Citations