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CHEBI:76232 - sodium meclofenamate monohydrate
| Formula | C14H10Cl2NO2.H2O.Na |
| Net Charge | 0 |
| Average Mass | 336.150 |
| Monoisotopic Mass | 335.00919 |
| SMILES | Cc1ccc(Cl)c(Nc2ccccc2C(=O)[O-])c1Cl.O.[Na+] |
| InChI | InChI=1S/C14H11Cl2NO2.Na.H2O/c1-8-6-7-10(15)13(12(8)16)17-11-5-3-2-4-9(11)14(18)19;;/h2-7,17H,1H3,(H,18,19);;1H2/q;+1;/p-1 |
| InChIKey | QHJLLDJTVQAFAN-UHFFFAOYSA-M |
| Roles Classification |
|---|
| Biological Roles: | analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor A lipoxygenase inhibitor that interferes with the action of arachidonate 5-lipoxygenase (EC 1.13.11.34). EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes. |
| Applications: | analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. antirheumatic drug A drug used to treat rheumatoid arthritis. anticonvulsant A drug used to prevent seizures or reduce their severity. non-steroidal anti-inflammatory drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. antipyretic A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| sodium meclofenamate monohydrate (CHEBI:76232) has part sodium meclofenamate (anhydrous) (CHEBI:6711) |
| sodium meclofenamate monohydrate (CHEBI:76232) has role analgesic (CHEBI:35480) |
| sodium meclofenamate monohydrate (CHEBI:76232) has role anticonvulsant (CHEBI:35623) |
| sodium meclofenamate monohydrate (CHEBI:76232) has role antineoplastic agent (CHEBI:35610) |
| sodium meclofenamate monohydrate (CHEBI:76232) has role antipyretic (CHEBI:35493) |
| sodium meclofenamate monohydrate (CHEBI:76232) has role antirheumatic drug (CHEBI:35842) |
| sodium meclofenamate monohydrate (CHEBI:76232) has role EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor (CHEBI:64964) |
| sodium meclofenamate monohydrate (CHEBI:76232) has role EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor (CHEBI:35544) |
| sodium meclofenamate monohydrate (CHEBI:76232) has role non-steroidal anti-inflammatory drug (CHEBI:35475) |
| sodium meclofenamate monohydrate (CHEBI:76232) is a hydrate (CHEBI:35505) |
| Synonyms | Source |
|---|---|
| meclofenamate sodium | ChemIDplus |
| sodium meclofenamate | ChemIDplus |
| Brand Names | Source |
|---|---|
| Lenidolor | ChEBI |
| Meclodol | ChEBI |
| Meclomen | KEGG DRUG |
| Manual Xrefs | Databases |
|---|---|
| D00169 | KEGG DRUG |
| Registry Numbers | Sources |
|---|---|
| Reaxys:14619562 | Reaxys |
| CAS:67254-91-5 | ChemIDplus |
| Citations |
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